Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 10/20 | 0.59 |
| ▸ | RAB9A | P51151 | 7/20 | 0.59 |
| ▸ | NPC1 | O15118 | 6/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ATM | Q13315 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | CCR1 | P32246 | 2/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.50 |
| ▸ | CCR8 | P51685 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | METAP1 | P53582 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.50 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | TP53 | P04637 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29945025 | 1.00 | KDM4E (0.59) | KDM4ERAB9ANPC1MAPTATM | |
| Propanol SCHEMBL27923176 | 0.87 | KDM4E (0.46) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL30921015 | 0.78 | GOT1 (0.33) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL1178875 | 0.74 | HSP90AA1 (0.34) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL6897351 | 0.74 | CYP19A1 (0.37) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL1424929 | 0.74 | KDM4E (1.00) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL22250429 | 0.74 | IDO1 (0.39) | KDM4ERAB9ANPC1MAPTATM | |
| SCHEMBL572719 | 0.70 | PDPK1 (0.45) | KDM4ERAB9ANPC1MAPTCYP1A2 | |
| Dipyridyl SCHEMBL29351528 | 0.69 | KDM4E (1.00) | KDM4ERAB9ANPC1MAPTATM | |
| Dipyridyl SCHEMBL29907716 | 0.69 | KDM4E (1.00) | KDM4ERAB9ANPC1MAPTATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220023277-A1 | CARBONIC ANHYDRASE TARGETING AGENTS AND METHODS OF USING SAME | VISEN MEDICAL, INC. | 2022-01-27 | — | — | US | claimed |
| US-12110283-B2 | Carbonic anhydrase targeting agents and methods of using same | VISEN MEDICAL, INC. (US) | 2024-10-08 | — | — | US | disclosed |
| US-20220023277-A1 | CARBONIC ANHYDRASE TARGETING AGENTS AND METHODS OF USING SAME | VISEN MEDICAL, INC. | 2022-01-27 | — | — | US | disclosed |
| US-20170334948-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | NOVALIX DEUTSCHLAND GMBH (DE) | 2017-11-23 | — | — | US | disclosed |
| EP-3216798-A2 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2017-09-13 | — | — | EP | disclosed |
| US-9745339-B2 | Ligands for antibody and Fc-fusion protein purification by affinity chromotography IV | NOVALIX DEUTSCHLAND GMBH (DE) | 2017-08-29 | — | — | US | disclosed |
| EP-2673285-B1 | KETOLIDE COMPOUNDS | WOCKHARDT LTD (IN) | 2017-07-19 | — | — | EP | disclosed |
| CN-105669803-A | KETOLIDE COMPOUNDS | 沃克哈特有限公司 | 2016-06-15 | — | — | CN | disclosed |
| US-20160083412-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2016-03-24 | — | — | US | disclosed |
| CN-103384676-B | Ketolactone compounds | WOCKHARDT LTD. (IN) | 2016-02-03 | — | — | CN | disclosed |
| US-20160009760-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2016-01-14 | — | — | US | disclosed |
| US-9175031-B2 | Ketolide compounds | WOCKHARDT LIMITED (IN) | 2015-11-03 | — | — | US | disclosed |
| CN-104395335-A | Ligands for antibody and fc-fusion protein purification by affinity chromotography iv | GRAFFINITY PHARMACEUTICALS GMBH | 2015-03-04 | — | — | CN | disclosed |
| EP-2812346-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | Graffinity Pharmaceuticals GmbH (DE) | 2014-12-17 | — | — | EP | disclosed |
| WO-2014020152-A1 | LIGANDS FOR APHERESIS AND IMMUNOABSORPTION | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2014-02-06 | — | — | WO | disclosed |
| US-20140005133-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2014-01-02 | — | — | US | disclosed |
| EP-2673285-A1 | KETOLIDE COMPOUNDS | Wockhardt Limited (IN) | 2013-12-18 | — | — | EP | disclosed |
| WO-2013117707-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2013-08-15 | — | — | WO | disclosed |
| WO-2012076989-A1 | KETOLIDE COMPOUNDS | WOCKHARDT LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170334948-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | FCGR1A, FCGR2A, FCGR3B | KDM4E 3660/4885RAB9A 3122/4885NPC1 3852/4885 |
| US-20160009760-A1 | LIGANDS FOR ANTIBODY AND FC-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMOTOGRAPHY IV | FCGR1A, FCGR2A, FCGR3B | KDM4E 3539/4885RAB9A 3135/4885NPC1 3817/4885 |
| US-12110283-B2 | Carbonic anhydrase targeting agents and methods of using same | CA4, CA12, CA9 | KDM4E 2005/4885RAB9A 2829/4885NPC1 1593/4885 |
| US-20160083412-A1 | KETOLIDE COMPOUNDS | AKR1C3, AKR1D1, AKR1C1 | KDM4E 313/4885RAB9A 891/4885NPC1 452/4885 |
| US-20140005133-A1 | KETOLIDE COMPOUNDS | AKR1C3, AKR1D1, AKR1C1 | KDM4E 298/4885RAB9A 1143/4885NPC1 458/4885 |
| US-20220023277-A1 | CARBONIC ANHYDRASE TARGETING AGENTS AND METHODS OF USING SAME | CA4, CA12, CA9 | KDM4E 2005/4885RAB9A 2829/4885NPC1 1593/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.