Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 14/20 | 0.37 |
| ▸ | FBP1 | P09467 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | AQP4 | P55087 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3068196 | 0.76 | FBP1 (0.48) | FBP1CYP1A2TSHR | |
| SCHEMBL29945025 | 0.74 | KDM4E (0.59) | CYP19A1CYP1A2TSHRKDM4ENPC1 | |
| SCHEMBL9905290 | 0.74 | KDM4E (0.59) | CYP19A1CYP1A2TSHRKDM4ENPC1 | |
| SCHEMBL25305371 | 0.70 | MAP4K4 (0.42) | MAPT | |
| SCHEMBL31150860 | 0.70 | MAP4K4 (0.42) | MAPT | |
| SCHEMBL24922738 | 0.67 | RXRA (0.36) | KDM4EMAPT | |
| SCHEMBL572719 | 0.67 | PDPK1 (0.45) | CYP1A2KDM4ENPC1MAPTRAB9A | |
| SCHEMBL15173885 | 0.66 | HPGDS (0.33) | FBP1 | |
| SCHEMBL969098 | 0.66 | NISCH (0.39) | CYP19A1FBP1CYP1A2KDM4E | |
| SCHEMBL1680218 | 0.64 | CYP2A6 (0.55) | CYP19A1CYP1A2KDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4436968-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | Ventus Therapeutics U.S., Inc. (US) | 2024-10-02 | — | — | EP | disclosed |
| WO-2023081441-A1 | HETEROCYCLIC COMPOUNDS AND USES THEREOF | VENTUS THERAPEUTICS U.S., INC. (US) | 2023-05-11 | — | — | WO | disclosed |
| US-6699853-B2 | PROTECTING USEFUL PLANTS AGAINST THE UNDESIRABLE ACTION OF HARMFUL INSECTS, ACARIDS AND NEMATODES, | HOECHST SCHERING AGREVO GMBH (DE) | 2004-03-02 | — | — | US | disclosed |
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | HARMSEN SVEN (DE) | 2003-08-28 | — | — | US | disclosed |
| US-6521610-B2 | For controlling harmful insects, acarina and nematodes | HOECHST SCHERING AGREVO GMBH (DE) | 2003-02-18 | — | — | US | disclosed |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | TIEBES JORG (DE) | 2002-01-31 | — | — | US | disclosed |
| US-6239160-B1 | 4-haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclylpyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | HOECHST SCHERING AGREVO GMBH (DE) | 2001-05-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030162812-A1 | 4-haloalkyl-3-heterocyclylpyridines, 4-haloalkyl-5-heterocyclyl-pyrimidines and 4-trifluoromethyl-3-oxadiazolylpyridines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HCK, HPD | CYP19A1 3546/4885FBP1 2309/4885TERT 2460/4885 |
| US-20020013326-A1 | 4-Haloalkyl-3-heterocyclylpyridines and 4-haloalkyl-5-heterocyclyl-pyrimidines, processes for their preparation, compositions comprising them, and their use as pesticides | DDT, HAX1, HDHD5 | CYP19A1 3676/4885FBP1 2726/4885TERT 1904/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.