Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | GCK | P35557 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9900202 | 0.77 | KMT2A (0.40) | KDM4EKMT2AMEN1HPGDHSD17B10 | |
| SCHEMBL19160402 | 0.70 | KMT2A (0.37) | KDM4EKMT2AMEN1HPGDHSD17B10 | |
| SCHEMBL9900107 | 0.69 | GLP1R (0.48) | HSD17B10GLP1RNPSR1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL10395304 | 0.64 | NPC1 (0.44) | KDM4EKMT2ANPSR1NPC1RAB9A | |
| SCHEMBL9900753 | 0.60 | ALDH1A1 (0.46) | KDM4EHPGDHSD17B10TDP1NPSR1 | |
| SCHEMBL9900886 | 0.60 | GLP1R (0.35) | KDM4ETDP1GLP1RALDH1A1 | |
| SCHEMBL8938457 | 0.60 | LPO (0.48) | KDM4EKMT2AMEN1HPGDHSD17B10 | |
| SCHEMBL19160376 | 0.60 | AXL (0.41) | KDM4EKMT2AMEN1HPGDHSD17B10 | |
| SCHEMBL8724916 | 0.60 | GCK (0.45) | KDM4EKMT2AMEN1HPGDHSD17B10 | |
| SCHEMBL9048818 | 0.60 | MYC (0.42) | KDM4EKMT2AMEN1HPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012076966-A1 | SUBSTITUTED THIENO [3,4-B] PYRAZINE COMPOUNDS | LUPIN LIMITED (IN) | 2012-06-14 | — | — | WO | claimed |
| WO-2012076966-A1 | SUBSTITUTED THIENO [3,4-B] PYRAZINE COMPOUNDS | LUPIN LIMITED (IN) | 2012-06-14 | — | — | WO | disclosed |