Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.48 |
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.48 |
| ▸ | NPBWR1 | P48145 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | GUSB | P08236 | 2/20 | 0.40 |
| ▸ | TNKS | O95271 | 1/20 | 0.40 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | ELANE | P08246 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28920099 | 0.82 | ALDH1A1 (0.33) | MAPTRAB9ASMN1; SMN2NPBWR1NPC1 | |
| SCHEMBL2227297 | 0.77 | METAP1 (0.52) | MAPTRAB9ASMN1; SMN2NPC1KMT2A | |
| SCHEMBL12881747 | 0.76 | ALDH1A1 (0.57) | MAPTRAB9ASMN1; SMN2NPBWR1NPC1 | |
| SCHEMBL7145501 | 0.76 | MMP2 (0.51) | MAPTRAB9ASMN1; SMN2NPBWR1NPC1 | |
| SCHEMBL11843651 | 0.75 | MAPT (0.36) | MAPTRAB9ASMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL19877854 | 0.75 | KDM4E (0.52) | MAPTRAB9ASMN1; SMN2NPBWR1NPC1 | |
| SCHEMBL9627673 | 0.72 | — | — | |
| SCHEMBL6054864 | 0.71 | RIPK1 (0.51) | MAPTSMN1; SMN2KMT2AMEN1ALDH1A1 | |
| SCHEMBL7838930 | 0.71 | CYP3A4 (0.36) | MAPTRAB9ASMN1; SMN2NPBWR1NPC1 | |
| SCHEMBL5578303 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240327444-A1 | Method for Purifying Nucleotides, Device for Purifying Nucleotides, Hy-Drophobic Reagent, and Hydrophobic Substrate | JAPAN SCIENCE AND TECHNOLOGY AGENCY (JP) | 2024-10-03 | — | — | US | disclosed |
| EP-4368628-A1 | METHOD FOR PURIFYING NUCLEOTIDES, DEVICE FOR PURIFYING NUCLEOTIDES, HYDROPHOBIC REAGENT, AND HYDROPHOBIC SUBSTRATE | Japan Science and Technology Agency (JP) | 2024-05-15 | — | — | EP | disclosed |
| CN-117858885-A | Method and device for purifying nucleotide, and hydrophobic reagent and hydrophobic substrate | 国立研究开发法人科学技术振兴机构 | 2024-04-09 | — | — | CN | disclosed |
| WO-2023282245-A1 | METHOD FOR PURIFYING NUCLEOTIDES, DEVICE FOR PURIFYING NUCLEOTIDES, HYDROPHOBIC REAGENT, AND HYDROPHOBIC SUBSTRATE | 国立研究開発法人科学技術振興機構 | 2023-01-12 | — | — | WO | disclosed |
| US-9834542-B2 | LXR modulators | BRISTO-MYERS SQUIBB COMPANY (US) | 2017-12-05 | — | — | US | disclosed |
| EP-2968275-B1 | LXR MODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2017-11-29 | — | — | EP | disclosed |
| US-20160304499-A1 | LXR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2016-10-20 | — | — | US | disclosed |
| EP-2968275-A1 | LXR MODULATORS | Bristol-Myers Squibb Company (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2014144037-A1 | LXR MODULATORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2014-09-18 | — | — | WO | disclosed |
| US-7863310-B2 | Kinase inhibitors | ELI LILLY AND COMPANY (US) | 2011-01-04 | — | — | US | disclosed |
| EP-1417204-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. du Pont de Nemours and Company (US) | 2004-05-12 | — | — | EP | disclosed |
| US-6627647-B1 | Substituted 1-(4-aminophenyl)imidazoles and their use as anti-inflammatory agents | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2003-09-30 | — | — | US | disclosed |
| WO-2003026664-A1 | 2-PHENYLAMINO-4- (5-PYRAZOLYLAMINO) -PYRAMIDINE DERIVATIVES AS KINASE INHIBITORS, IN PARTICULAR, SRC KINASE INHIBITORS | BAYER CORPORATION (US) | 2003-04-03 | — | — | WO | disclosed |
| WO-2003016304-A1 | ORTHO-HETEROCYCLIC SUBSTITUTED ARYL AMIDES FOR CONTROLLING INVERTEBRATE PESTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |
| WO-2001070703-A2 | SUBSTITUTED 1-(4-AMINOPHENYL)IMIDAZOLES AND THEIR USE AS ANTI-INFLAMMATORY AGENTS | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2001-09-27 | — | — | WO | disclosed |
| EP-0365907-A1 | Process for the preparation of p-nitrophenyl imidazoles | BASF Aktiengesellschaft (DE) | 1990-05-02 | — | — | EP | disclosed |
| EP-0131973-B1 | NEW AMIDINE DERIVATIVES OF 2-SUBSTITUTED 4-PHENILIMIDAZOLE | ISTITUTO DE ANGELI S.p.A. (IT) | 1989-08-02 | — | — | EP | disclosed |
| US-4649150-A | ANTISECRETORY AGENTS | ISTITUTO DE ANGELI, S.P.A. (IT) | 1987-03-10 | — | — | US | disclosed |
| EP-0131973-A1 | New amidine derivatives of 2-substituted 4-phenilimidazole | ISTITUTO DE ANGELI S.p.A. (IT) | 1985-01-23 | — | — | EP | disclosed |
| US-4272538-A | 5-Nitro-imidazole with antiprotozoic activity | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1981-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160304499-A1 | LXR MODULATORS | NR1H2, NR1H3, NR1H4 | MAPT 3581/4885RAB9A 3452/4885SMN1; SMN2 4731/4885 |
| US-20240327444-A1 | Method for Purifying Nucleotides, Device for Purifying Nucleotides, Hy-Drophobic Reagent, and Hydrophobic Substrate | NUDT1, SAMHD1, PNP | MAPT 4208/4885RAB9A 3139/4885SMN1; SMN2 2055/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.