SCHEMBL9908271

SCHEMBL9908271

CCNC(=O)COCC(N)=O

nearest known ligand 0.42

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
FAAH O00519 2/20 0.42
MCL1 Q07820 1/20 0.39
RAB9A P51151 3/20 0.39
HPGD P15428 1/20 0.39
NPC1 O15118 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
LMNA P02545 2/20 0.38
KDM4E B2RXH2 2/20 0.36
PKM P14618 1/20 0.36
MAPK1 P28482 1/20 0.36
TSHR P16473 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CTSD P07339 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16173906 0.89 MCL1 (0.46) FAAHMCL1RAB9AHPGDNPC1
SCHEMBL13007887 0.88 MEN1 (0.40) FAAHRAB9AHPGDNPC1SMN1; SMN2
SCHEMBL27410666 0.86 FAAH (0.33) FAAHMCL1RAB9AHPGDNPC1
SCHEMBL14392989 0.83 CTSD (0.43) FAAHMCL1RAB9AHPGDNPC1
SCHEMBL26227327 0.83 MCL1 (0.45) FAAHMCL1RAB9AHPGDNPC1
SCHEMBL13707242 0.82
SCHEMBL14415956 0.80 FAAH (0.43) FAAHMCL1RAB9AHPGDNPC1
SCHEMBL13402313 0.80 CES2 (0.42) FAAHMCL1RAB9AHPGDNPC1
SCHEMBL15616271 0.80 MCL1 (0.40) FAAHMCL1RAB9AHPGDNPC1
SCHEMBL14393226 0.80 RAB9A (0.43) FAAHMCL1RAB9AHPGDNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3797796-A1 ANTIBODY-DRUG CONJUGATE AND APPLICATION THEREOF Mabplex International, Ltd. (CN) 2021-03-31 EP disclosed
US-9981043-B2 Analgesic conjugates REGENTS OF THE UNIVERSITY OF MINNESOTA (US) 2018-05-29 US disclosed
US-8197793-B2 Methods of radiofluorination of biologically active vectors GE HEALTHCARE AS (NO) 2012-06-12 US disclosed
US-8197793-B2 Methods of radiofluorination of biologically active vectors GE HEALTHCARE AS (NO) 2012-06-12 US disclosed
US-20100068139-A1 Methods of radiofluorination of biologically active vectors GE HEALTHCARE AS (NO) 2010-03-18 US disclosed
US-20100068139-A1 Methods of radiofluorination of biologically active vectors GE HEALTHCARE AS (NO) 2010-03-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100068139-A1 Methods of radiofluorination of biologically active vectors DOHH, VGF, HNRNPH3 FAAH 216/4885MCL1 558/4885RAB9A 111/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.