Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | GNAI3 | P08754 | 9/20 | 0.47 |
| ▸ | GNAI1 | P63096 | 9/20 | 0.47 |
| ▸ | GNAO1 | P09471 | 8/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18760893 | 0.87 | MMP2 (0.40) | GNAI3GNAI1GNAO1MEN1KMT2A | |
| SCHEMBL15601957 | 0.84 | L3MBTL1 (0.60) | L3MBTL1GNAI3GNAI1GNAO1MEN1 | |
| SCHEMBL21018564 | 0.81 | L3MBTL1 (0.53) | L3MBTL1GNAI3GNAI1GNAO1MEN1 | |
| SCHEMBL10290423 | 0.79 | L3MBTL1 (0.58) | L3MBTL1GNAI3GNAI1GNAO1MEN1 | |
| SCHEMBL11466803 | 0.79 | L3MBTL1 (0.58) | L3MBTL1GNAI3GNAI1GNAO1MEN1 | |
| SCHEMBL14845706 | 0.78 | MEN1 (0.54) | L3MBTL1GNAI3GNAI1GNAO1MEN1 | |
| SCHEMBL17037504 | 0.78 | CHRNB2 (0.33) | KMT2A | |
| SCHEMBL21140125 | 0.78 | GNAI3 (0.53) | L3MBTL1GNAI3GNAI1GNAO1MEN1 | |
| SCHEMBL13097061 | 0.77 | L3MBTL1 (0.60) | L3MBTL1GNAI3GNAI1GNAO1MEN1 | |
| SCHEMBL21886617 | 0.76 | L3MBTL1 (0.51) | L3MBTL1GNAI3GNAI1GNAO1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170107511-A1 | OLIGONUCLEOTIDE END CAPS | BANK OF AMERICA, N.A. | 2017-04-20 | — | — | US | disclosed |
| US-9512164-B2 | Oligonucleotide end caps | ALNYLAM PHARMACEUTICALS, INC. (US) | 2016-12-06 | — | — | US | disclosed |
| US-20120142101-A1 | OLIGONUCLEOTIDE END CAPS | ALNYLAM PHARMACEUTICALS, INC. (US) | 2012-06-07 | — | — | US | disclosed |