Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 6/20 | 0.45 |
| ▸ | NOS3 | P29474 | 5/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.41 |
| ▸ | HTR3B | O95264 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 2/20 | 0.41 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.41 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.41 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.41 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.41 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.41 |
| ▸ | PLAU | P00749 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.38 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11568501 | 0.75 | HTR3E (0.50) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL16374609 | 0.74 | NOS1 (0.54) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL5140496 | 0.74 | NOS1 (0.54) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL31513660 | 0.73 | HTR3E (0.48) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL30424922 | 0.73 | HTR3E (0.48) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL13292290 | 0.71 | NOS1 (0.56) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL398432 | 0.70 | HTR3E (0.44) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL398431 | 0.70 | HTR3E (0.44) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL28674580 | 0.70 | HTR3E (0.44) | NOS1NOS3HTR3EHTR3BHTR3A | |
| SCHEMBL1743759 | 0.70 | HTR3E (0.44) | NOS1NOS3HTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160060365-A1 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. | 2016-03-03 | — | — | US | disclosed |
| US-20120142560-A1 | HEPARAN SULFATE SYNTHESIS | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 2012-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160060365-A1 | HEPARAN SULFATE SYNTHESIS | HPSE, STT3B, DDOST | NOS1 4573/4885NOS3 4296/4885HTR3E 3764/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.