Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | XBP1 | P17861 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5746668 | 0.93 | LMNA (0.43) | HTR7LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL15051115 | 0.84 | HTR7 (0.41) | HTR7LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL15050377 | 0.84 | HTR7 (0.41) | HTR7LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL15050375 | 0.84 | HTR7 (0.41) | HTR7LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL12964104 | 0.84 | HRH3 (0.42) | LMNAALDH1A1MEN1KMT2AXBP1 | |
| SCHEMBL15051113 | 0.84 | HTR7 (0.41) | HTR7LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL15050374 | 0.84 | HTR7 (0.41) | HTR7LMNAALDH1A1MEN1KMT2A | |
| SCHEMBL6679827 | 0.81 | POLB (0.53) | LMNAALDH1A1MEN1KMT2ANPSR1 | |
| SCHEMBL12224067 | 0.81 | AOC3 (0.43) | LMNAALDH1A1MEN1KMT2AAOC3 | |
| SCHEMBL18503058 | 0.81 | AOC3 (0.52) | HTR7ALDH1A1MEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198487-B2 | Method for lithium exchange reactions | LONZA AG (CH) | 2012-06-12 | — | — | US | disclosed |
| US-20100113839-A1 | METHOD FOR LITHIUM EXCHANGE REACTIONS | LONZA AG (CH) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113839-A1 | METHOD FOR LITHIUM EXCHANGE REACTIONS | SLC6A5, SLC6A9, SLC6A6 | HTR7 3946/4885LMNA 1170/4885ALDH1A1 4332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.