Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853285 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL284364 | 1.00 | — | — | |
| SCHEMBL8919 | 1.00 | — | — | |
| SCHEMBL8424624 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL22448471 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL24054976 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL13122851 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL10274898 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL21120437 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL12094717 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CYTOKINETICS, INC. | 2023-04-20 | — | — | US | disclosed |
| US-20220380520-A1 | STRONG BINDING METAL-CHELATING RESINS USING MACROCYCLE MOLECULES | SACHEM, INC. | 2022-12-01 | — | — | US | disclosed |
| WO-2022136844-A1 | N-(PYRIDIN-2-YL)-6,7,8,9-TETRAHYDRO-5H-5,8-EPIMINOCYCLOHEPTA[C]PYRIDINE-10-CARBOXAMIDE DERIVATIVES AND SIMILAR COMPOUNDS AS GPR65 MODULATORS FOR THE TREATMENT OF CANCER | Pathios Therapeutics Limited (GB) | 2022-06-30 | — | — | WO | disclosed |
| US-20220144839-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | PAHR THERAPEUTICS, INC. | 2022-05-12 | — | — | US | disclosed |
| WO-2022090724-A1 | NOVEL COMPOUNDS | SITRYX THERAPEUTICS LIMITED (GB) | 2022-05-05 | — | — | WO | disclosed |
| US-11134676-B2 | Anti-microbial particles and methods of use thereof | NOBIO LTD. (IL) | 2021-10-05 | — | — | US | disclosed |
| US-20210295005-A1 | INTERACTIVE BIOMETRIC TOUCH SCANNER | Orchid Sound Technologies LLC | 2021-09-23 | — | — | US | disclosed |
| EP-3326715-B1 | OXALIC ACID MONOAMIDE LIGAND, AND USES THEREOF IN COUPLING REACTION OF COPPER-CATALYZED ARYL HALOGEN SUBSTITUTE | CE PHARM CO LTD (CN) | 2021-09-15 | — | — | EP | disclosed |
| US-20210163464-A1 | PYRIDINE COMPOUND | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2021-06-03 | — | — | US | disclosed |
| US-11023704-B2 | Interactive biometric touch scanner | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) | 2021-06-01 | — | — | US | disclosed |
| US-8207286-B2 | Methods for preparing polyurethanes | PPG INDUSTRIES OHIO, INC (US) | 2012-06-26 | — | — | US | disclosed |
| US-8198298-B2 | Pyrrolo[2,3-b]pyridine derivatives active as kinase inhibitors | PFIZER ITALIA S.R.L. (IT) | 2012-06-12 | — | — | US | disclosed |
| WO-2012050015-A1 | POLYMERIZABLE FLUORINE-CONTAINING SULFONATE, FLUORINE-CONTAINING SULFONATE RESIN, RESIST COMPOSITION AND PATTERN-FORMING METHOD USING SAME | セントラル硝子株式会社 (JP) | 2012-04-19 | — | — | WO | disclosed |
| US-20110136857-A1 | PYRROLE[2,3-B]PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS | PFIZER ITALIA S.R.L. (IT) | 2011-06-09 | — | — | US | disclosed |
| US-7879955-B2 | Compositions including a polythioether | PRC-DESOTO INTERNATIONAL, INC. | 2011-02-01 | — | — | US | disclosed |
| US-20100048852-A1 | High impact poly(urethane urea) polysulfides | PPG INDUSTRIES OHIO, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20090281268-A1 | METHODS FOR PREPARING POLYURETHANES | PPG INDUSTRIES OHIO, INC. (US) | 2009-11-12 | — | — | US | disclosed |
| CN-101448866-A | Natural oil based polyols with intrinsic surpactancy for polyurethane foaming | DOW GLOBAL TECHNOLOGIES INC (US) | 2009-06-03 | — | — | CN | disclosed |
| US-20090012244-A1 | COMPOSITIONS INCLUDING A POLYTHIOETHER | PRC-DESOTO INTERNATIONAL, INC. (US) | 2009-01-08 | — | — | US | disclosed |
| US-20080245263-A1 | Phase change inks containing colorant compounds | XEROX CORPORATION | 2008-10-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144839-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | AHR, ARNT, IDO1 | ALDH1A1 316/4885TDP1 2915/4885TSHR 974/4885 |
| US-20210163464-A1 | PYRIDINE COMPOUND | RET, ABL1, ROS1 | ALDH1A1 1589/4885TDP1 1797/4885TSHR 1789/4885 |
| US-20230116972-A1 | CD38 MODULATORS AND METHODS OF USE THEREOF | CD38, CXCR4, FCGRT | ALDH1A1 358/4885TDP1 587/4885TSHR 2152/4885 |
| US-20110136857-A1 | PYRROLE[2,3-B]PYRIDINE DERIVATIVES ACTIVE AS KINASE INHIBITORS | MAP3K6, MAP3K3, MAP3K15 | ALDH1A1 4198/4885TDP1 633/4885TSHR 3922/4885 |
| US-11134676-B2 | Anti-microbial particles and methods of use thereof | LPO, MPO, CAPG | ALDH1A1 3866/4885TDP1 3229/4885TSHR 4502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.