Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL853285 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL284364 | 1.00 | — | — | |
| SCHEMBL9909079 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL8919 | 1.00 | — | — | |
| SCHEMBL8424624 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL22448471 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL24054976 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL13122851 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL21120437 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 | |
| SCHEMBL12094717 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TSHRCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160237059-A1 | HETEROCYCLIC SUBSTITUTED TRIFLUOROMETHYL PYRIMIDINONES AND THEIR USE | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2016-08-18 | — | — | US | disclosed |
| US-8399094-B2 | Multilayer laminated articles including polyurethane and/or poly(ureaurethane) layers and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-8399559-B2 | Polyurethanes, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2013-03-19 | — | — | US | disclosed |
| US-8349986-B2 | Poly(ureaurethane)s, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. (US) | 2013-01-08 | — | — | US | disclosed |
| US-8207286-B2 | Methods for preparing polyurethanes | PPG INDUSTRIES OHIO, INC (US) | 2012-06-26 | — | — | US | disclosed |
| US-7879955-B2 | Compositions including a polythioether | PRC-DESOTO INTERNATIONAL, INC. | 2011-02-01 | — | — | US | disclosed |
| US-20100184899-A1 | THIOETHERS, METHODS FOR THEIR PREPARATION, AND COMPOSITIONS INCLUDING SUCH THIOETHERS | PRC-DESOTO INTERNATIONAL, INC. (US) | 2010-07-22 | — | — | US | disclosed |
| US-20100086792-A1 | POLYIMIDE PRECURSOR, ITS COMPOSITION AND POLYIMIDE LAMINATE | ETERNAL CHEMICAL CO., LTD. (TW) | 2010-04-08 | — | — | US | disclosed |
| US-20100048852-A1 | High impact poly(urethane urea) polysulfides | PPG INDUSTRIES OHIO, INC. (US) | 2010-02-25 | — | — | US | disclosed |
| US-20090280709-A1 | Polyurethanes, Articles and Coatings Prepared Therefrom and Methods of Making the Same | PPG INDUSTRIES OHIO, INC. (US) | 2009-11-12 | — | — | US | disclosed |
| US-20080139684-A1 | PROCESS FOR PREPARING A POLYURETHANE UREA POLISHING PAD | PPG INDUSTRIES OHIO, INC. (US) | 2008-06-12 | — | — | US | disclosed |
| US-20070256597-A1 | Poly(ureaurethane)s, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-11-08 | — | — | US | disclosed |
| US-7291063-B2 | Polyurethane urea polishing pad | PPG INDUSTRIES OHIO, INC. (US) | 2007-11-06 | — | — | US | disclosed |
| US-20070248827-A1 | Multilayer laminated articles including polyurethane and/or poly(ureaurethane) layers and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-10-25 | — | — | US | disclosed |
| US-20070225468-A1 | Polyurethanes prepared from polyester polyols and/or polycaprolactone polyols, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-09-27 | — | — | US | disclosed |
| US-20070155942-A1 | Polyurethanes, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-07-05 | — | — | US | disclosed |
| US-20070149748-A1 | Poly(ureaurethane)s, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-06-28 | — | — | US | disclosed |
| US-20070148471-A1 | Impact resistant polyurethane and poly(ureaurethane) articles and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-06-28 | — | — | US | disclosed |
| US-20070149747-A1 | Poly(ureaurethane)s, articles and coatings prepared therefrom and methods of making the same | PPG INDUSTRIES OHIO, INC. | 2007-06-28 | — | — | US | disclosed |
| US-20070142606-A1 | Polyurethane (ureas) and sulfur-containing polyurethane (ureas) methods of preparation | PPG INDUSTRIES OHIO, INC. | 2007-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100184899-A1 | THIOETHERS, METHODS FOR THEIR PREPARATION, AND COMPOSITIONS INCLUDING SUCH THIOETHERS | TTPA, CTH, GSTO1 | ALDH1A1 1900/4885TDP1 2879/4885TSHR 2588/4885 |
| US-20160237059-A1 | HETEROCYCLIC SUBSTITUTED TRIFLUOROMETHYL PYRIMIDINONES AND THEIR USE | REN, GLS, FIBP | ALDH1A1 1089/4885TDP1 2701/4885TSHR 3100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.