Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CARM1 | Q86X55 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | PDIA6 | Q15084 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9909784 | 0.87 | PARP10 (0.41) | MAOBMAOA | |
| SCHEMBL4841319 | 0.78 | MTNR1A (0.41) | CARM1PLAUPDIA6 | |
| SCHEMBL9909818 | 0.73 | CARM1 (0.38) | CARM1 | |
| SCHEMBL8091595 | 0.68 | DRD2 (0.51) | CARM1PDIA6 | |
| SCHEMBL11306679 | 0.66 | HTR1A (0.48) | CARM1 | |
| SCHEMBL18185301 | 0.66 | IDO1 (0.39) | — | |
| SCHEMBL25155134 | 0.66 | PDIA6 (0.42) | CARM1PLAUPDIA6 | |
| SCHEMBL23735695 | 0.65 | CARM1 (0.47) | CARM1 | |
| SCHEMBL454009 | 0.65 | KDM4E (0.45) | CARM1PLAUPDIA6 | |
| SCHEMBL21601187 | 0.65 | CARM1 (0.45) | CARM1MAOBPDIA6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1548024-B1 | PYRAZOLE DERIVATIVES, MEDICINAL COMPOSITION CONTAINING THE SAME, MEDICINAL USE THEREOF, AND INTERMEDIATE FOR PRODUCTION THEREOF | KISSEI PHARMACEUTICAL (JP) | 2012-06-06 | — | — | EP | disclosed |