Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | USP2 | O75604 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25410314 | 0.76 | KDM4E (0.36) | ALDH1A1TSHRUSP2LMNAKDM4E | |
| SCHEMBL5154099 | 0.75 | TSHR (0.39) | ALDH1A1TSHRUSP2CA2CA9 | |
| SCHEMBL6621065 | 0.74 | ALDH1A1 (0.61) | ALDH1A1TSHRUSP2LMNAKDM4E | |
| SCHEMBL9709607 | 0.74 | NLRP3 (0.32) | — | |
| SCHEMBL1606138 | 0.72 | TSHR (0.65) | ALDH1A1TSHRUSP2LMNAKDM4E | |
| SCHEMBL10151688 | 0.71 | CA1 (0.59) | ALDH1A1TSHRUSP2LMNAKDM4E | |
| SCHEMBL1606611 | 0.71 | TSHR (0.62) | ALDH1A1TSHRUSP2LMNAKDM4E | |
| SCHEMBL20495987 | 0.71 | TSHR (0.62) | ALDH1A1TSHRUSP2LMNAKDM4E | |
| SCHEMBL11176516 | 0.71 | TSHR (0.62) | ALDH1A1TSHRUSP2LMNAKDM4E | |
| SCHEMBL9432188 | 0.71 | TSHR (0.62) | ALDH1A1TSHRUSP2LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198390-B2 | Self assembled grafted polymeric layer for use in biosensor technology | IMEC (BE) | 2012-06-12 | — | — | US | disclosed |
| US-20100204415-A1 | SELFASSEMBLED GRAFTED POLYMERIC LAYER FOR USE IN BIOSENSOR TECHNOLOGY | IMEC (BE) | 2010-08-12 | — | — | US | disclosed |