Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25410314 | 0.80 | KDM4E (0.36) | — | |
| SCHEMBL9911084 | 0.74 | ALDH1A1 (0.35) | — | |
| SCHEMBL29601357 | 0.70 | CACNA2D1 (0.30) | — | |
| SCHEMBL9709906 | 0.70 | TSHR (0.34) | — | |
| SCHEMBL9709564 | 0.70 | ALDH1A1 (0.38) | — | |
| SCHEMBL19285468 | 0.68 | CA1 (0.40) | — | |
| SCHEMBL19285469 | 0.68 | CA1 (0.40) | — | |
| SCHEMBL23671019 | 0.68 | CA1 (0.40) | — | |
| SCHEMBL9500520 | 0.67 | TSHR (0.61) | NLRP3 | |
| SCHEMBL9709901 | 0.67 | SLC1A2 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153214-A | Treating cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0493324-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1992-07-01 | — | — | EP | disclosed |
| US-5025025-A | Cardiovascular disorders | CIBA-GEIGY CORPORATION (US) | 1991-06-18 | — | — | US | disclosed |
| EP-0405391-A1 | Certain (arylsulfonamido- and pyridyl- or imidazolyl-)-substituted carboxylic acids and derivatives thereof | CIBA-GEIGY AG (CH) | 1991-01-02 | — | — | EP | disclosed |