Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR | Q13258 | 15/20 | 0.52 |
| ▸ | BRAF | P15056 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | STAT6 | P42226 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9912204 | 0.84 | PTGDR (0.56) | PTGDRBRAFPIK3CAPIK3CBPIK3CG | |
| SCHEMBL9912237 | 0.83 | PTGDR (0.52) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL4489730 | 0.81 | PTGDR (0.79) | PTGDR | |
| SCHEMBL9912281 | 0.81 | BRAF (0.61) | PTGDRBRAFALDH1A1SMN1; SMN2 | |
| SCHEMBL13895137 | 0.79 | PTGDR (0.64) | PTGDRALDH1A1SMN1; SMN2 | |
| SCHEMBL13894999 | 0.77 | ALDH1A1 (0.47) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL9912250 | 0.76 | PTGDR (0.85) | PTGDR | |
| SCHEMBL9912189 | 0.76 | BCHE (0.47) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL9912276 | 0.74 | PTGDR (0.63) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 | |
| SCHEMBL9912203 | 0.73 | PTGDR (0.66) | PTGDRPIK3CAPIK3CBPIK3CGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8193183-B2 | 2,6-substituted-4-monosubstitutedamino-pyrimidine as prostaglandin D2 receptor antagonists | AVENTIS PHARMACEUTICALS INC. (US) | 2012-06-05 | — | — | US | disclosed |