Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.47 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 7/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.45 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.45 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.44 |
| ▸ | VNN1 | O95497 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15751641 | 0.85 | KDM4E (0.51) | L3MBTL1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL787524 | 0.84 | KDM4E (0.50) | KDM4EMAPT | |
| SCHEMBL5841560 | 0.80 | POLB (0.60) | L3MBTL1KDM4EMAPTPOLBLMNA | |
| SCHEMBL10584591 | 0.80 | MEN1 (0.56) | L3MBTL1KDM4EMAPTKMT2AMEN1 | |
| SCHEMBL798050 | 0.79 | ESR1 (0.58) | L3MBTL1KDM4EMAPTPOLBMTNR1A | |
| SCHEMBL28691182 | 0.76 | POLB (0.62) | POLB | |
| SCHEMBL2142240 | 0.75 | RAB9A (0.58) | POLBSMN1; SMN2 | |
| SCHEMBL787766 | 0.74 | MAPT (0.61) | L3MBTL1KDM4EMAPTPOLBMTNR1A | |
| SCHEMBL30134679 | 0.74 | MAPT (0.61) | L3MBTL1KDM4EMAPTPOLBMTNR1A | |
| SCHEMBL30335932 | 0.74 | POLB (0.73) | KDM4EMAPTPOLBLMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2451781-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | Givaudan SA (CH) | 2012-05-16 | — | — | EP | claimed |
| WO-2011004016-A1 | PYRIDINE DERIVATIVES WITH UMAMI FLAVOUR | GIVAUDAN SA (CH) | 2011-01-13 | — | — | WO | claimed |