Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OGA | O60502 | 4/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TK2 | O00142 | 1/20 | 0.31 |
| ▸ | TK1 | P04183 | 1/20 | 0.31 |
| ▸ | PIM1 | P11309 | 1/20 | 0.31 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.31 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.31 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.31 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.31 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.31 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14025413 | 1.00 | OGA (0.36) | OGAPDE4DSLC5A2ALDH1A1TSHR | |
| SCHEMBL23640105 | 1.00 | OGA (0.36) | OGAPDE4DSLC5A2ALDH1A1TSHR | |
| SCHEMBL26309581 | 1.00 | OGA (0.36) | OGAPDE4DSLC5A2ALDH1A1TSHR | |
| SCHEMBL23640147 | 0.83 | OGA (0.35) | OGAPDE4DSLC5A2TK2TK1 | |
| SCHEMBL20154818 | 0.78 | OGA (0.41) | OGAPDE4DSLC5A2ALDH1A1TSHR | |
| SCHEMBL12694172 | 0.78 | OGA (0.41) | OGAPDE4DSLC5A2ALDH1A1TSHR | |
| SCHEMBL14257090 | 0.78 | OGA (0.37) | OGAPDE4DSLC5A2LMNAHIF1A | |
| SCHEMBL13656418 | 0.78 | OGA (0.37) | OGAPDE4DSLC5A2LMNAHIF1A | |
| SCHEMBL16216989 | 0.78 | OGA (0.37) | OGAPDE4DSLC5A2LMNAHIF1A | |
| SCHEMBL17225755 | 0.78 | OGA (0.37) | OGAPDE4DSLC5A2LMNAHIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9469864-B2 | Reversible natural product glycosyltransferase-catalyzed reactions, compounds and related methods | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2016-10-18 | — | — | US | disclosed |
| US-20150141294-A1 | REVERSIBLE NATURAL PRODUCT GLYCOSYLTRANSFERASE-CATALYZED REACTIONS, COMPOUNDS AND RELATED METHODS | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2015-05-21 | — | — | US | disclosed |
| US-8841092-B2 | Reversible natural product glycosyltransferase-catalyzed reactions, compounds and related methods | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2014-09-23 | — | — | US | disclosed |
| US-20130012466-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-01-10 | — | — | US | disclosed |
| US-20120264924-A1 | Glycorandomization and Production of Novel Novobiocin Analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-10-18 | — | — | US | disclosed |
| US-8232254-B2 | Colchicine glycosylated to include a sugar moiety on a methoxyamino-appended colchicine; cytolysis equivalent to paclitaxel and doxorubicin; stabilizers of tubulin formation; anticarcinogenic -arthritic agents; Mediterranean fever, amyloidosis, scleroderma, irritable bowel syndrome or gout | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-31 | — | — | US | disclosed |
| US-8232254-B2 | Colchicine glycosylated to include a sugar moiety on a methoxyamino-appended colchicine; cytolysis equivalent to paclitaxel and doxorubicin; stabilizers of tubulin formation; anticarcinogenic -arthritic agents; Mediterranean fever, amyloidosis, scleroderma, irritable bowel syndrome or gout | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-07-31 | — | — | US | disclosed |
| US-8198419-B2 | Glycorandomization and production of novel erythromycin analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2012-06-12 | — | — | US | disclosed |
| US-20110124850-A1 | Glycorandomization and Production of Novel Vancomycin Analogs | THORSON JON | 2011-05-26 | — | — | US | disclosed |
| US-20090275485-A1 | Reversible Natural Product Glycosyltransferase-Catalyzed Reactions, Compounds and Related Methods | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2009-11-05 | — | — | US | disclosed |
| WO-2008067039-A9 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | WISCONSIN ALUMNI RES FOUND (US) | 2008-10-16 | — | — | WO | disclosed |
| US-20080171787-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-17 | — | — | US | disclosed |
| US-20080171787-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-07-17 | — | — | US | disclosed |
| WO-2008067039-A2 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-06-05 | — | — | WO | disclosed |
| US-7348309-B2 | Glycorandomization and production of novel vancomycin analogs | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080171787-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | TUBB6, TUBB, TUBA1C | OGA 487/4885PDE4D 3446/4885SLC5A2 1034/4885 |
| US-20110124850-A1 | Glycorandomization and Production of Novel Vancomycin Analogs | NMT1, NMT2, B3GNT2 | OGA 64/4885PDE4D 2257/4885SLC5A2 418/4885 |
| US-20130012466-A1 | COLCHICINE NEOGLYCOSIDES AND METHODS FOR THEIR SYNTHESIS AND USE | TUBB6, TUBB, TUBA1C | OGA 487/4885PDE4D 3446/4885SLC5A2 1034/4885 |
| US-20090275485-A1 | Reversible Natural Product Glycosyltransferase-Catalyzed Reactions, Compounds and Related Methods | UGGT1, ENGASE, CSGALNACT1 | OGA 109/4885PDE4D 2653/4885SLC5A2 961/4885 |
| US-20120264924-A1 | Glycorandomization and Production of Novel Novobiocin Analogs | NMT2, NMT1, NAMPT | OGA 90/4885PDE4D 1405/4885SLC5A2 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.