Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | HPGD | P15428 | 6/20 | 0.53 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.51 |
| ▸ | KCNK9 | Q9NPC2 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915151 | 0.87 | ALDH1A1 (0.54) | SMN1; SMN2ALDH1A1HPGDKCNK3KCNK9 | |
| SCHEMBL9274738 | 0.80 | ALOX15 (0.52) | SMN1; SMN2ALDH1A1HPGDKCNK3KCNK9 | |
| SCHEMBL11570198 | 0.78 | HDAC3 (0.50) | ALDH1A1KCNK3KCNK9KMT2ACYP1A2 | |
| SCHEMBL9915156 | 0.78 | POLB (0.57) | SMN1; SMN2ALDH1A1HPGDKMT2ACYP1A2 | |
| SCHEMBL11940437 | 0.76 | HPGD (0.49) | SMN1; SMN2ALDH1A1HPGDKCNK3KCNK9 | |
| SCHEMBL12323189 | 0.75 | NPC1 (0.75) | SMN1; SMN2ALDH1A1HPGDKCNK3KCNK9 | |
| SCHEMBL28176461 | 0.75 | ALDH1A1 (0.69) | SMN1; SMN2ALDH1A1HPGDKCNK3KCNK9 | |
| SCHEMBL9915114 | 0.74 | CES1 (0.45) | SMN1; SMN2ALDH1A1HPGDKMT2ACYP3A4 | |
| SCHEMBL3627482 | 0.72 | CES2 (0.61) | SMN1; SMN2ALDH1A1HPGDKCNK3KCNK9 | |
| SCHEMBL29231950 | 0.72 | HPGD (0.66) | SMN1; SMN2ALDH1A1HPGDKCNK3KCNK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096504-B2 | Controlled chemical release of hydrogen sulfide | WASHINGTON STATE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130253051-A1 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | WASHINGTON STATE UNIVERSITY (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2012075242-A2 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253051-A1 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | GSR, AR, GRHPR | SMN1; SMN2 407/4885ALDH1A1 2368/4885HPGD 815/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.