SCHEMBL9915151

SCHEMBL9915151

Cc1ccccc1C(=O)SNC(=O)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
HPGD P15428 5/20 0.53
POLB P06746 1/20 0.53
KCNK3 O14649 1/20 0.51
KCNK9 Q9NPC2 1/20 0.51
L3MBTL1 Q9Y468 2/20 0.46
NPC1 O15118 2/20 0.46
RAB9A P51151 2/20 0.46
KMT2A Q03164 1/20 0.46
TP53 P04637 1/20 0.44
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44
CYP1A2 P05177 1/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9915109 0.87 SMN1; SMN2 (0.54) ALDH1A1SMN1; SMN2HPGDPOLBKCNK3
SCHEMBL9274738 0.80 ALOX15 (0.52) ALDH1A1SMN1; SMN2HPGDPOLBKCNK3
SCHEMBL9915154 0.80 RAB9A (0.63) ALDH1A1SMN1; SMN2HPGDPOLBKCNK3
SCHEMBL11570198 0.78 HDAC3 (0.50) ALDH1A1POLBKCNK3KCNK9NPC1
SCHEMBL9915156 0.78 POLB (0.57) ALDH1A1SMN1; SMN2HPGDPOLBL3MBTL1
SCHEMBL15206652 0.77 ERCC5 (0.50) ALDH1A1SMN1; SMN2HPGDPOLBL3MBTL1
SCHEMBL27515367 0.76 ALOX15 (0.56) ALDH1A1SMN1; SMN2HPGDPOLBKCNK3
SCHEMBL9915149 0.75 SMN1; SMN2 (0.63) ALDH1A1SMN1; SMN2POLBKCNK3KCNK9
SCHEMBL12323189 0.75 NPC1 (0.75) ALDH1A1SMN1; SMN2HPGDPOLBKCNK3
SCHEMBL28176461 0.75 ALDH1A1 (0.69) ALDH1A1SMN1; SMN2HPGDPOLBKCNK3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9096504-B2 Controlled chemical release of hydrogen sulfide WASHINGTON STATE UNIVERSITY (US) 2015-08-04 US disclosed
US-20130253051-A1 CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE WASHINGTON STATE UNIVERSITY (US) 2013-09-26 US disclosed
WO-2012075242-A2 CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) 2012-06-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130253051-A1 CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE GSR, AR, GRHPR ALDH1A1 2368/4885SMN1; SMN2 407/4885HPGD 815/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.