Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | KCNK3 | O14649 | 2/20 | 0.56 |
| ▸ | KCNK9 | Q9NPC2 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.47 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9915156 | 0.83 | POLB (0.57) | SMN1; SMN2POLBMEN1KMT2AMAPT | |
| SCHEMBL9274738 | 0.82 | ALOX15 (0.52) | SMN1; SMN2POLBMEN1KMT2AKCNK3 | |
| SCHEMBL11570198 | 0.81 | HDAC3 (0.50) | POLBMEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL9915155 | 0.81 | KCNK3 (0.56) | SMN1; SMN2MEN1KMT2AKCNK3KCNK9 | |
| SCHEMBL9915152 | 0.80 | RAB9A (0.66) | SMN1; SMN2POLBMEN1KMT2AKCNK3 | |
| SCHEMBL24931103 | 0.78 | SMN1; SMN2 (1.00) | SMN1; SMN2POLBMEN1KMT2AKCNK3 | |
| SCHEMBL21653856 | 0.78 | SMN1; SMN2 (0.79) | SMN1; SMN2POLBMEN1KMT2AKCNK3 | |
| SCHEMBL10282557 | 0.76 | HDAC8 (0.65) | SMN1; SMN2POLBMEN1KMT2AKCNK3 | |
| SCHEMBL9915151 | 0.75 | ALDH1A1 (0.54) | SMN1; SMN2POLBKMT2AKCNK3KCNK9 | |
| SCHEMBL779316 | 0.75 | PARP1 (0.61) | SMN1; SMN2POLBMEN1KMT2AKCNK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9096504-B2 | Controlled chemical release of hydrogen sulfide | WASHINGTON STATE UNIVERSITY (US) | 2015-08-04 | — | — | US | disclosed |
| US-20130253051-A1 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | WASHINGTON STATE UNIVERSITY (US) | 2013-09-26 | — | — | US | disclosed |
| WO-2012075242-A2 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | WASHINGTON STATE UNIVERSITY RESEARCH FOUNDATION (US) | 2012-06-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130253051-A1 | CONTROLLED CHEMICAL RELEASE OF HYDROGEN SULFIDE | GSR, AR, GRHPR | SMN1; SMN2 407/4885POLB 3149/4885MEN1 3672/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.