Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16748696 | 0.77 | PLA2G4B (0.43) | HPGDALDH1A1 | |
| SCHEMBL15279016 | 0.76 | — | — | |
| SCHEMBL9915471 | 0.72 | SMN1; SMN2 (0.40) | HPGDSMN1; SMN2MAPTCYP1A2CYP2C9 | |
| SCHEMBL14136577 | 0.69 | USP2 (0.45) | HPGDSMN1; SMN2MAPTCYP1A2CYP2C9 | |
| SCHEMBL15279055 | 0.67 | CDK1 (0.35) | PPARGPPARDPPARA | |
| SCHEMBL16748648 | 0.67 | CDK1 (0.38) | SMN1; SMN2CYP1A2 | |
| SCHEMBL16748804 | 0.63 | NR1H4 (0.46) | SMN1; SMN2LMNAKMT2APPARD | |
| SCHEMBL9915516 | 0.63 | PLA2G4B (0.41) | HPGDALDH1A1 | |
| SCHEMBL14818596 | 0.63 | CDK1 (0.40) | MAPTLMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9915324 | 0.63 | CDK1 (0.38) | SMN1; SMN2MAPTCYP1A2CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012073138-A1 | MONOBACTAMS | PFIZER INC. (US) | 2012-06-07 | — | — | WO | disclosed |