Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.43 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PPARD | Q03181 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15279003 | 0.81 | DAO (0.43) | LMNA | |
| SCHEMBL9915491 | 0.77 | SMYD3 (0.45) | NR1H4LMNASMN1; SMN2TP53KMT2A | |
| SCHEMBL9915434 | 0.76 | NR1H4 (0.44) | NR1H4EPHX2LMNASMN1; SMN2PTGER4 | |
| SCHEMBL16748696 | 0.76 | PLA2G4B (0.43) | TP53TSHR | |
| SCHEMBL15279000 | 0.75 | L3MBTL1 (0.41) | — | |
| SCHEMBL9915326 | 0.73 | LMNA (0.48) | NR1H4EPHX2LMNASMN1; SMN2PTGER4 | |
| SCHEMBL9915484 | 0.72 | MAPT (0.49) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL9915516 | 0.72 | PLA2G4B (0.41) | TP53TSHR | |
| SCHEMBL9915519 | 0.72 | MEN1 (0.44) | LMNASMN1; SMN2KMT2A | |
| SCHEMBL16748652 | 0.71 | MEN1 (0.42) | NR1H4LMNASMN1; SMN2TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2646436-B1 | MONOBACTAMS | PFIZER (US) | 2015-05-27 | — | — | EP | disclosed |