SCHEMBL9915682

SCHEMBL9915682

C=CC(=O)Oc1ccc(N(c2ccccc2)c2ccc(C=C(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.40
PTGS2 P35354 2/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 4/20 0.39
KMT2A Q03164 4/20 0.39
ALDH1A1 P00352 4/20 0.39
KDM4E B2RXH2 2/20 0.39
HPGD P15428 2/20 0.39
MEN1 O00255 1/20 0.39
HSP90AA1 P07900 1/20 0.39
RAB9A P51151 2/20 0.39
CYP19A1 P11511 1/20 0.39
CYP11B2 P19099 1/20 0.39
TSHR P16473 1/20 0.37
TRPM8 Q7Z2W7 1/20 0.36
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
ESR1 P03372 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36
NPC1 O15118 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2609801 0.99 CYP2D6 (0.42) THRBPTGS2CYP2D6MAPTKMT2A
SCHEMBL13777756 0.99 CYP2D6 (0.42) THRBPTGS2CYP2D6MAPTKMT2A
SCHEMBL9915754 0.99 CYP2D6 (0.42) THRBPTGS2CYP2D6MAPTKMT2A
SCHEMBL9915809 0.99 PTGS2 (0.41) THRBPTGS2CYP2D6MAPTKMT2A
SCHEMBL11987116 0.97 ALDH1A1 (0.42) THRBPTGS2CYP2D6MAPTKMT2A
SCHEMBL10102845 0.96 KMT2A (0.40) THRBPTGS2CYP2D6MAPTKMT2A
SCHEMBL13818605 0.96 KMT2A (0.40) THRBPTGS2CYP2D6MAPTKMT2A
SCHEMBL12234131 0.93 CYP2D6 (0.36) THRBPTGS2CYP2D6MAPTKMT2A
SCHEMBL9915695 0.93 PTGS2 (0.47) THRBPTGS2CYP2D6MAPTKMT2A
SCHEMBL4407659 0.93 CYP2D6 (0.40) THRBPTGS2CYP2D6MAPTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8927183-B2 Electrophotographic photoreceptor, method for preparing the electrophotographic photoreceptor, and image forming method and apparatus and process cartridge using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2015-01-06 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-8669030-B2 Electrophotographic photoreceptor, and image forming method and apparatus using the same RICOH COMPANY, LIMITED (JP) 2014-03-11 US disclosed
US-20140030644-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-01-30 US disclosed
US-20140030644-A1 IMAGE BEARING MEMBER AND IMAGE FORMING APPARATUS RICOH COMPANY, LTD. (JP) 2014-01-30 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8507163-B2 Method of manufacturing image bearing member, image bearing member, and image forming apparatus RICOH COMPANY, LTD. (JP) 2013-08-13 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-8486595-B2 Image bearing member, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2013-07-16 US disclosed
US-20070059619-A1 Electrophotographic photoconductor, image forming apparatus, image forming method, and process cartridge RICOH COMPANY, LTD. (JP) 2007-03-15 US disclosed
US-20070042281-A1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-02-22 US disclosed
US-20070042281-A1 Electrophotographic photoreceptor, and image forming apparatus and process cartridge therefor using the electrophotographic photoreceptor RICOH COMPANY, LTD. (JP) 2007-02-22 US disclosed
US-7179573-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-20 US disclosed
US-7175957-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-7175957-B2 Electrophotographic photoconductor, and image forming process, image forming apparatus and process cartridge for an image forming apparatus using the same RICOH COMPANY, LTD. (JP) 2007-02-13 US disclosed
US-20070031746-A1 Electrophotographic photoconductor, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2007-02-08 US disclosed
US-20070031746-A1 Electrophotographic photoconductor, process cartridge, and image forming method RICOH COMPANY, LTD. (JP) 2007-02-08 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed
US-20070009818-A1 Electrophotographic photoreceptor and method of preparing the photoreceptor, and image forming method, image forming apparatus and process cartridge therefor using the photoreceptor RICOH COMPANY, LTD. (JP) 2007-01-11 US disclosed