SCHEMBL9915857

SCHEMBL9915857

N#CC(C#N)=C(c1ccc(O)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MMP3 P08254 3/20 0.56
BCL2L1 Q07817 1/20 0.56
CYP19A1 P11511 3/20 0.49
MEN1 O00255 3/20 0.48
KMT2A Q03164 3/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
RAB9A P51151 1/20 0.48
DEGS1 O15121 1/20 0.45
ESR1 P03372 5/20 0.44
ESR2 Q92731 3/20 0.42
NTSR1 P30989 1/20 0.42
ADORA2A P29274 1/20 0.41
ADORA1 P30542 1/20 0.41
EGFR P00533 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9068811 0.92 SMN1; SMN2 (0.43) MMP3BCL2L1CYP19A1MEN1KMT2A
SCHEMBL9068815 0.84 CYP1A2 (0.54) MEN1KMT2ALMNAMAPTADORA2A
SCHEMBL12966771 0.84 SMN1; SMN2 (0.42) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL9915858 0.84 MEN1 (0.38) MMP3BCL2L1CYP19A1MEN1KMT2A
SCHEMBL9068805 0.80 TRIM24 (0.44) MEN1KMT2ALMNAMAPTRAB9A
SCHEMBL9068816 0.80 CES2 (0.46) MEN1KMT2AMAPTESR1ESR2
SCHEMBL13209451 0.80 RAB9A (0.47) MEN1KMT2AMAPTRAB9AADORA2A
SCHEMBL134312 0.80 ALDH1A1 (0.52) CYP19A1MEN1KMT2ALMNAMAPT
Cyanate SCHEMBL27613565 0.78 MMP3 (0.75) MMP3BCL2L1MEN1KMT2ALMNA
SCHEMBL17368206 0.78 RAB9A (0.68) MMP3BCL2L1CYP19A1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8199291-B2 Liquid crystal display device having polymer-stabilized blue phase liquid crystal layer and transparent films FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-8049850-B2 Liquid crystal display device, optical compensatory sheet, and polarizer and liquid crystal display device employing the same FUJIFILM CORPORATION (JP) 2011-11-01 US disclosed
US-7951430-B2 Cellulose acylate film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-05-31 US disclosed
US-20100143613-A1 Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
US-20090322997-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-12-31 US disclosed
US-20090290100-A1 Cellulose Acylate Film, Method of Producing the Same, Cellulose Derivative Film, Optically Compensatory Film Using the Same, Optically-Compensatory Film Incorporating Polarizing Plate, Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-11-26 US disclosed
US-20090202823-A1 Cellulose Ester Film, Polarizing Plate and Display MURAKAMI TAKASHI 2009-08-13 US disclosed
US-20090122243-A1 Liquid Crystal Display Device, Optical Compensatory Sheet, and Polarizer and Liquid Crystal Display Device Employing the Same FUJIFILM CORPORATION (JP) 2009-05-14 US disclosed
US-20090086125-A1 Process for producing cellulose acylate film, cellulose acylate film, optically- compensatory film, polarizing plate and liquid-crystal display device FUJIFILM CORPORATIN (JP) 2009-04-02 US disclosed
US-20090051856-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-02-26 US disclosed
US-20080138540-A1 Polymer Film, Optically-Compensatory Film, Process for Producing the Same, Polarizing Plate and Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed