SCHEMBL9915858

SCHEMBL9915858

N#CC(C#N)=C(c1ccc(I)cc1)c1ccc(-c2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
SMN1; SMN2 Q16637 3/20 0.37
MAPT P10636 2/20 0.37
WDR5 P61964 1/20 0.37
RAB9A P51151 2/20 0.37
CYP1A2 P05177 2/20 0.37
FFAR1 O14842 1/20 0.37
LMNA P02545 1/20 0.37
HIF1A Q16665 1/20 0.37
TPMT P51580 1/20 0.36
ALDH1A1 P00352 2/20 0.36
NPC1 O15118 1/20 0.35
CTDSP1 Q9GZU7 1/20 0.35
MMP3 P08254 1/20 0.34
BCL2L1 Q07817 1/20 0.34
PTPN1 P18031 1/20 0.34
GSK3B P49841 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CDC25B P30305 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9068811 0.91 SMN1; SMN2 (0.43) MEN1KMT2ASMN1; SMN2MAPTWDR5
SCHEMBL9915857 0.84 MMP3 (0.56) MEN1KMT2AMAPTRAB9ALMNA
SCHEMBL12966771 0.82 SMN1; SMN2 (0.42) MEN1KMT2ASMN1; SMN2MAPTRAB9A
SCHEMBL9068815 0.82 CYP1A2 (0.54) MEN1KMT2ASMN1; SMN2MAPTWDR5
SCHEMBL13209451 0.78 RAB9A (0.47) MEN1KMT2ASMN1; SMN2MAPTRAB9A
SCHEMBL9068816 0.78 CES2 (0.46) MEN1KMT2ASMN1; SMN2MAPTALDH1A1
SCHEMBL9068805 0.78 TRIM24 (0.44) MEN1KMT2ASMN1; SMN2MAPTRAB9A
SCHEMBL134312 0.78 ALDH1A1 (0.52) MEN1KMT2AMAPTRAB9ACYP1A2
Water SCHEMBL7348466 0.76 ALDH1A1 (0.56) SMN1; SMN2MAPTWDR5CYP1A2TPMT
SCHEMBL24029558 0.73 ALDH1A1 (0.60) SMN1; SMN2MAPTWDR5CYP1A2TPMT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8199291-B2 Liquid crystal display device having polymer-stabilized blue phase liquid crystal layer and transparent films FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
US-8049850-B2 Liquid crystal display device, optical compensatory sheet, and polarizer and liquid crystal display device employing the same FUJIFILM CORPORATION (JP) 2011-11-01 US disclosed
US-7951430-B2 Cellulose acylate film, polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2011-05-31 US disclosed
US-20100143613-A1 Cellulose Acylate Film, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2010-06-10 US disclosed
US-20090322997-A1 LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-12-31 US disclosed
US-20090290100-A1 Cellulose Acylate Film, Method of Producing the Same, Cellulose Derivative Film, Optically Compensatory Film Using the Same, Optically-Compensatory Film Incorporating Polarizing Plate, Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2009-11-26 US disclosed
US-20090202823-A1 Cellulose Ester Film, Polarizing Plate and Display MURAKAMI TAKASHI 2009-08-13 US disclosed
US-20090122243-A1 Liquid Crystal Display Device, Optical Compensatory Sheet, and Polarizer and Liquid Crystal Display Device Employing the Same FUJIFILM CORPORATION (JP) 2009-05-14 US disclosed
US-20090086125-A1 Process for producing cellulose acylate film, cellulose acylate film, optically- compensatory film, polarizing plate and liquid-crystal display device FUJIFILM CORPORATIN (JP) 2009-04-02 US disclosed
US-20090051856-A1 CELLULOSE ACYLATE FILM, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2009-02-26 US disclosed
US-20080138540-A1 Polymer Film, Optically-Compensatory Film, Process for Producing the Same, Polarizing Plate and Liquid-Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-12 US disclosed