SCHEMBL9915910

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL9901072	0.78	LTB4R (0.44)	LTB4RPLA2G4AGRIK1CES1TRPA1
	SCHEMBL9915916	0.73	NLRP3 (0.42)	GRIK1TRPA1MMP8HDAC3HDAC1
	SCHEMBL9915921	0.72	GRIK1 (0.40)	LTB4RGRIK1TRPA1MMP8HDAC3
	SCHEMBL5610385	0.70	HDAC3 (0.52)	GRIK1TRPA1MMP8HDAC3HDAC1
	SCHEMBL4575395	0.70	RIPK1 (0.52)	GRIK1HDAC3HDAC1HDAC2HDAC8
	SCHEMBL5833581	0.69	TRPA1 (0.56)	GRIK1TRPA1HDAC3HDAC1HDAC2
	SCHEMBL8849468	0.69	HDAC3 (0.50)	GRIK1TRPA1HDAC3HDAC1HDAC2
	SCHEMBL1952256	0.68	PLA2G4A (0.52)	LTB4RPLA2G4ACES1TRPA1SMN1; SMN2
	SCHEMBL1337921	0.66	HTR2A (0.48)	GRIK1TRPA1HDAC3HDAC1HDAC2
	SCHEMBL11753178	0.66	HDAC3 (0.47)	GRIK1TRPA1HDAC3HDAC1HDAC2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.