SCHEMBL9916153

SCHEMBL9916153

CC(C)c1ccc(-c2ccc3c(c2)oc2ccccc23)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 1/20 0.57
PARP1 P09874 1/20 0.57
TNKS2 Q9H2K2 1/20 0.57
HDAC6 Q9UBN7 1/20 0.57
PARP2 Q9UGN5 1/20 0.57
AHR P35869 2/20 0.51
MMP12 P39900 1/20 0.47
MMP13 P45452 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
MAPT P10636 2/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 1/20 0.46
HPGD P15428 1/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
SMN1; SMN2 Q16637 2/20 0.46
GAA P10253 1/20 0.46
CYP2C9 P11712 2/20 0.44
NQO1 P15559 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9916205 1.00 TNKS (0.57) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL9916179 1.00 TNKS (0.57) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL9916196 0.95 TNKS (0.54) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL9916176 0.95 TNKS (0.54) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL9916207 0.95 TNKS (0.54) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL9916190 0.95 TNKS (0.54) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL9916189 0.92 TNKS (0.48) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL9916163 0.92 TNKS (0.48) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL9916184 0.90 TNKS (0.57) TNKSPARP1TNKS2HDAC6PARP2
SCHEMBL9916174 0.90 TNKS (0.57) TNKSPARP1TNKS2HDAC6PARP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME SAMSUNG DISPLAY CO., LTD. (KR) 2023-04-27 US disclosed
US-20220223796-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT CONTAINING ORGANIC COMPOUND, AND ELECTRONIC DEVICE SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2022-07-14 US disclosed
US-10930859-B2 Phenanthroquinazoline-core compounds DOW GLOBAL TECHNOLOGIES LLC (US) 2021-02-23 US disclosed
US-20200303659-A1 PHENANTHROQUINAZOLINE-CORE COMPOUNDS DOW GLOBAL TECHNOLOGIES LLC (US) 2020-09-24 US disclosed
US-20180111940-A1 IMIDAZOPYRAZINE DERIVED COMPOUNDS FOR ELECTRONIC DEVICES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-26 US disclosed
US-20180111940-A1 IMIDAZOPYRAZINE DERIVED COMPOUNDS FOR ELECTRONIC DEVICES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-26 US disclosed
US-20180108845-A1 CYCLIC UREA COMPOUNDS FOR ELECTRONIC DEVICES DOW GLOBAL TECHNOLOGIES LLC (US) 2018-04-19 US disclosed
US-20170162790-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2017-06-08 US disclosed
US-9614160-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2017-04-04 US disclosed
US-9278926-B2 Aromatic amine derivative, and organic electroluminescent element comprising same IDEMITSU KOSAN CO., LTD. (JP) 2016-03-08 US disclosed
US-9278926-B2 Aromatic amine derivative, and organic electroluminescent element comprising same IDEMITSU KOSAN CO., LTD. (JP) 2016-03-08 US disclosed
US-20160064669-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2016-03-03 US disclosed
US-9260390-B2 Aromatic amine derivatives and organic electroluminescent elements using same IDEMITSU KOSAN CO., LTD. (JP) 2016-02-16 US disclosed
US-20120248426-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-10-04 US disclosed
US-20120248426-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-10-04 US disclosed
US-20120146014-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME IDEMITSU KOSAN CO., LTD. (JP) 2012-06-14 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (10 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170162790-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME RER1, NR4A1, REL TNKS 4121/4885PARP1 2443/4885TNKS2 4382/4885
US-20230130537-A1 LIGHT EMITTING DEVICE AND AMINE COMPOUND FOR THE SAME MAOA, MAOB, AOC2 TNKS 3909/4885PARP1 1364/4885TNKS2 3535/4885
US-20180111940-A1 IMIDAZOPYRAZINE DERIVED COMPOUNDS FOR ELECTRONIC DEVICES KCNJ2, KCNJ5, IKZF1 TNKS 2766/4885PARP1 1287/4885TNKS2 2812/4885
US-20180108845-A1 CYCLIC UREA COMPOUNDS FOR ELECTRONIC DEVICES SLC14A1, ODC1, UROD TNKS 4287/4885PARP1 3587/4885TNKS2 4516/4885
US-10930859-B2 Phenanthroquinazoline-core compounds TOP1, TOP2A, BICRA TNKS 361/4885PARP1 27/4885TNKS2 512/4885
US-20120146014-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME PNMT, TYR, AOC2 TNKS 3400/4885PARP1 2473/4885TNKS2 3512/4885
US-20160064669-A1 AROMATIC AMINE DERIVATIVES AND ORGANIC ELECTROLUMINESCENT ELEMENTS USING SAME PNMT, TYR, AOC2 TNKS 3400/4885PARP1 2473/4885TNKS2 3512/4885
US-20220223796-A1 ORGANIC COMPOUND, ELECTRONIC COMPONENT CONTAINING ORGANIC COMPOUND, AND ELECTRONIC DEVICE EXOC1, EXOC4, CHRM1 TNKS 3652/4885PARP1 622/4885TNKS2 4160/4885
US-20120248426-A1 AROMATIC AMINE DERIVATIVE, AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAME AOC2, AHR, AOC3 TNKS 4145/4885PARP1 1715/4885TNKS2 4012/4885
US-20200303659-A1 PHENANTHROQUINAZOLINE-CORE COMPOUNDS TOP1, TOP2A, BICRA TNKS 361/4885PARP1 27/4885TNKS2 512/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.