Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL2 | P10415 | 1/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 2/20 | 0.35 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12879656 | 0.88 | KDM4E (0.38) | MAOASRD5A2KDM4ENPC1ALDH1A1 | |
| SCHEMBL12219219 | 0.88 | KDM4E (0.38) | MAOASRD5A2KDM4ENPC1ALDH1A1 | |
| SCHEMBL10144710 | 0.88 | CHRM1 (0.37) | SRD5A2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL12879655 | 0.80 | ESR1 (0.40) | MAOASRD5A2KDM4ENPC1ALDH1A1 | |
| SCHEMBL9920546 | 0.77 | MAOA (0.35) | MAOAMAOBSRD5A2KDM4ENPC1 | |
| SCHEMBL13138273 | 0.77 | ALDH1A1 (0.42) | MAOASRD5A2KDM4ENPC1ALDH1A1 | |
| SCHEMBL12879658 | 0.77 | ALDH1A1 (0.42) | MAOASRD5A2KDM4ENPC1ALDH1A1 | |
| SCHEMBL30210980 | 0.77 | ALDH1A1 (0.42) | MAOASRD5A2KDM4ENPC1ALDH1A1 | |
| SCHEMBL12879669 | 0.77 | PNMT (0.38) | SRD5A2KDM4ENPC1ALDH1A1LMNA | |
| SCHEMBL13138261 | 0.76 | ALDH1A1 (0.43) | MAOBKDM4EALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9458182-B2 | Silyl- and heteroatom-substituted compounds selected from carbazoles, dibenzofurans, dibenzothiophenes and dibenzophospholes, and use thereof in organic electronics | BASF SE (DE) | 2016-10-04 | — | — | US | disclosed |
| US-8691401-B2 | Bridged benzimidazole-carbene complexes and use thereof in OLEDS | BASF SE (DE) | 2014-04-08 | — | — | US | disclosed |
| US-8362246-B2 | Bispyrimidines for electronic applications | BASF SE (DE) | 2013-01-29 | — | — | US | disclosed |
| US-20120149904-A1 | BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS | BASF SE (DE) | 2012-06-14 | — | — | US | disclosed |
| US-20120012821-A1 | SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS | BASF SE (DE) | 2012-01-19 | — | — | US | disclosed |
| US-20110253988-A1 | BRIDGED BENZIMIDAZOLE-CARBENE COMPLEXES AND USE THEREOF IN OLEDS | BASF SE (DE) | 2011-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149904-A1 | BISPYRIMIDINES FOR ELECTRONIC APPLICATIONS | DPYD, TYMP, TYMS | BCL2 3141/4885MCL1 2173/4885MAOA 1525/4885 |
| US-20110253988-A1 | BRIDGED BENZIMIDAZOLE-CARBENE COMPLEXES AND USE THEREOF IN OLEDS | CCND1, DRD2, CCND2 | BCL2 692/4885MCL1 2367/4885MAOA 271/4885 |
| US-20120012821-A1 | SILYL- AND HETEROATOM-SUBSTITUTED COMPOUNDS SELECTED FROM CARBAZOLES, DIBENZOFURANS, DIBENZOTHIOPHENES AND DIBENZOPHOSPHOLES, AND USE THEREOF IN ORGANIC ELECTRONICS | DDT, CDKL1, CDK2 | BCL2 1752/4885MCL1 2831/4885MAOA 1501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.