SCHEMBL9920681

SCHEMBL9920681

Cc1cc(-c2cccc(-n3c4ccccc4c4ccccc43)c2)c2ccc3c(-c4cccc(-n5c6ccccc6c6ccccc65)c4)cc(-c4cccc(-n5c6ccccc6c6ccccc65)c4)c4ccc1c2c43

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
HTR1A P08908 1/20 0.35
HTR7 P34969 1/20 0.35
HSD17B10 Q99714 2/20 0.33
ASH1L Q9NR48 1/20 0.33
ALKBH5 Q6P6C2 1/20 0.33
FTO Q9C0B1 1/20 0.33
RXFP1 Q9HBX9 1/20 0.33
NQO2 P16083 1/20 0.33
ALDH1A1 P00352 3/20 0.32
PKM P14618 1/20 0.32
KMT2A Q03164 4/20 0.31
IL1R1 P14778 1/20 0.31
PLA2G10 O15496 1/20 0.31
MEN1 O00255 3/20 0.31
GAA P10253 1/20 0.31
CHEK1 O14757 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9920794 0.97 KDM4E (0.44) KDM4EL3MBTL1ATMHTR1AHTR7
SCHEMBL9920644 0.86 KDM4E (0.44) KDM4EL3MBTL1ATMHSD17B10ALKBH5
SCHEMBL9939617 0.83 L3MBTL1 (0.42) KDM4EL3MBTL1ATMHSD17B10ASH1L
SCHEMBL9920640 0.83 L3MBTL1 (0.46) KDM4EL3MBTL1ATMHSD17B10ASH1L
SCHEMBL9920986 0.83 HTR7 (0.38) KDM4EL3MBTL1ATMHTR1AHTR7
SCHEMBL9920634 0.83 KDM4E (0.39) KDM4EL3MBTL1ATMHSD17B10ASH1L
SCHEMBL9920645 0.82 KDM4E (0.41) KDM4EL3MBTL1ATMHSD17B10ALDH1A1
SCHEMBL9920792 0.81 ALDH1A1 (0.36) KDM4EL3MBTL1ATMHSD17B10RXFP1
SCHEMBL9920790 0.81 L3MBTL1 (0.44) KDM4EL3MBTL1ATMHSD17B10ASH1L
SCHEMBL9920964 0.81 L3MBTL1 (0.44) KDM4EL3MBTL1ATMHSD17B10ASH1L

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463352-B1 Light emitting device material and light emitting device TORAY INDUSTRIES (JP) 2018-05-02 EP disclosed
EP-1942171-B1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES (JP) 2018-04-18 EP disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-20140061629-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2014-03-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
US-8502201-B2 Light-emitting element TORAY INDUSTRIES, INC. (JP) 2013-08-06 US disclosed
EP-2463352-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
EP-2463351-A2 Light emitting device material and light emitting device Toray Industries, Inc. (JP) 2012-06-13 EP disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20110121268-A1 LIGHT-EMITTING ELEMENT TORAY INDUSTRIES, INC. (JP) 2011-05-26 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
US-20090096356-A1 Light-emitting device material and light-emitting device TORAY INDUSTRIES, INC. (JP) 2009-04-16 US disclosed
EP-1942171-A1 LIGHT-EMITTING DEVICE MATERIAL AND LIGHT-EMITTING DEVICE TORAY INDUSTRIES, INC. (JP) 2008-07-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090096356-A1 Light-emitting device material and light-emitting device PRMT9, CCNL2, MRPL9 KDM4E 2433/4885L3MBTL1 283/4885ATM 1983/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.