Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.77 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.71 |
| ▸ | PTPN5 | P54829 | 1/20 | 0.71 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.63 |
| ▸ | LMNA | P02545 | 5/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | POLB | P06746 | 3/20 | 0.63 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.63 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.63 |
| ▸ | MAPT | P10636 | 5/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.57 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.55 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9921129 | 0.89 | PHGDH (0.87) | PHGDHDUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL21292847 | 0.88 | DUSP3 (0.82) | PHGDHDUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL21292850 | 0.88 | DUSP3 (0.82) | PHGDHDUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL22245277 | 0.87 | PHGDH (1.00) | PHGDHDUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL21309254 | 0.87 | PHGDH (1.00) | PHGDHDUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL686244 | 0.86 | DUSP3 (0.62) | PHGDHDUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL686334 | 0.85 | DUSP3 (0.61) | PHGDHDUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL686258 | 0.84 | LMNA (0.73) | PHGDHKMT2ALMNATDP1KDM4E | |
| SCHEMBL683720 | 0.84 | DUSP3 (0.76) | PHGDHDUSP3PTPN5PTPN11KMT2A | |
| SCHEMBL684813 | 0.84 | DUSP3 (0.76) | PHGDHDUSP3PTPN5PTPN11KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148682-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | DOW AGROSCIENCES LLC (US) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010075-A1 | SYNERGISTIC FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, SOD3 | PHGDH 1735/4885DUSP3 858/4885PTPN5 1027/4885 |
| US-20120148682-A1 | FUNGICIDAL COMPOSITIONS INCLUDING HYDRAZONE DERIVATIVES AND COPPER | SOD1, CYP51A1, CYP4Z1 | PHGDH 1393/4885DUSP3 1332/4885PTPN5 1156/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.