Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | PARP15 | Q460N3 | 3/20 | 0.46 |
| ▸ | PARP10 | Q53GL7 | 3/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21309791 | 0.97 | ALDH1A1 (0.50) | MEN1KMT2AALDH1A1PARP15PARP10 | |
| SCHEMBL19218155 | 0.92 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1PARP15PARP10 | |
| SCHEMBL21309642 | 0.92 | ALDH1A1 (0.51) | MEN1KMT2AALDH1A1PARP15PARP10 | |
| SCHEMBL3468807 | 0.89 | PARP15 (0.54) | MEN1KMT2APARP15PARP10PARP2 | |
| SCHEMBL13270486 | 0.87 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1PARP15PARP10 | |
| SCHEMBL13261805 | 0.87 | ALDH1A1 (0.46) | MEN1KMT2AALDH1A1PARP15PARP10 | |
| SCHEMBL13267949 | 0.85 | ALDH1A1 (0.49) | MEN1KMT2AALDH1A1DRD2DRD4 | |
| SCHEMBL19214417 | 0.83 | ALDH1A1 (0.51) | KMT2AALDH1A1PARP15PARP10PARP2 | |
| SCHEMBL9764680 | 0.83 | KMT2A (0.58) | MEN1KMT2AALDH1A1PARP15PARP10 | |
| SCHEMBL2296496 | 0.83 | DRD2 (0.49) | MEN1KMT2APARP15PARP10DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | FERRO THERAPEUTICS INC (US) | 2023-02-09 | — | — | US | disclosed |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | MOLECULAR SKIN THERAPEUTICS, INC. | 2019-08-29 | — | — | US | disclosed |
| US-20120149830-A1 | POLYESTER FILM AND METHOD OF FABRICATING THE SAME | INDUSTRIAL TECHNOLOGY RESEARCH INSTITUTE (TW) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230039846-A1 | COMPOUNDS AND METHODS OF USE | AIFM2, GPX4, GPX1 | MEN1 1772/4885KMT2A 2510/4885ALDH1A1 1254/4885 |
| US-20190263802-A1 | COMPOUNDS AND METHOD OF USE | AIFM2, GPX4, GPX1 | MEN1 1681/4885KMT2A 2475/4885ALDH1A1 1190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.