SCHEMBL16016346

SCHEMBL16016346

C1=Cc2c(n(-c3cccc(-c4cccc(-c5cccc(-c6cccc(-n7c8ccccc8c8ncccc87)c6)n5)n4)c3)c3ccccc23)CN1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR1A P08908 1/20 0.33
HTR7 P34969 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16016433 0.87 CYP11B1 (0.32)
SCHEMBL16016381 0.85 MAOA (0.32)
SCHEMBL9921890 0.84 HTR1A (0.39) HTR1AHTR7
SCHEMBL9922052 0.81 MAP4K1 (0.31)
SCHEMBL10048449 0.80 KARS1 (0.30)
SCHEMBL16016426 0.80
SCHEMBL4561486 0.79 HTR1A (0.35) HTR1AHTR7
SCHEMBL4562423 0.78
SCHEMBL12919193 0.78 TUBB4A (0.37) HTR1AHTR7
SCHEMBL13892617 0.76 METAP2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2463288-B1 Compound having substituted pyridyl group and pyridoindole ring structure linked through phenylene group, and organic electroluminescent device HODOGAYA CHEMICAL CO LTD (JP) 2014-09-10 EP disclosed