Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOB | P04114 | 2/20 | 0.40 |
| ▸ | MTTP | P55157 | 2/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.39 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.39 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.38 |
| ▸ | MC5R | P33032 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.35 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924069 | 0.94 | GRM4 (0.38) | APOBMTTPPRCPSLC6A9GRM4 | |
| SCHEMBL9924332 | 0.93 | SLC6A9 (0.41) | SLC6A9GRM4EPHX2TP53MEN1 | |
| SCHEMBL9924070 | 0.93 | GRM4 (0.40) | APOBMTTPPRCPSLC6A9GRM4 | |
| SCHEMBL17206710 | 0.92 | MEN1 (0.38) | APOBMTTPPRCPSLC6A9GRM4 | |
| SCHEMBL9924087 | 0.91 | HSD11B1 (0.39) | SLC6A9GRM4SLC6A5EPHX2MC5R | |
| SCHEMBL9924215 | 0.89 | SLC6A9 (0.41) | SLC6A9GRM4SLC6A5EPHX2MC5R | |
| SCHEMBL9924257 | 0.87 | GRM5 (0.42) | APOBMTTPEPHX2MEN1KMT2A | |
| SCHEMBL9924255 | 0.86 | GRM4 (0.36) | SLC6A9GRM4SLC6A5EPHX2MC5R | |
| SCHEMBL9924329 | 0.85 | SLC6A9 (0.40) | SLC6A9EPHX2TP53KMT2AALDH1A1 | |
| SCHEMBL9924083 | 0.85 | NPC1 (0.44) | GRM4MC5RTP53MDM2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |