Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | CCR3 | P51677 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.37 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.37 |
| ▸ | LHCGR | P22888 | 3/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | CXCR6 | O00574 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924090 | 0.93 | APOB (0.40) | SLC6A9MAPK14KMT2ATP53MAPT | |
| SCHEMBL9924329 | 0.92 | SLC6A9 (0.40) | SLC6A9MAPK14KMT2ACCR3LMNA | |
| SCHEMBL9924069 | 0.91 | GRM4 (0.38) | SLC6A9KMT2ATP53MAPTGRM4 | |
| SCHEMBL9924070 | 0.90 | GRM4 (0.40) | SLC6A9KMT2AGRM4EPHX2MEN1 | |
| SCHEMBL9924257 | 0.90 | GRM5 (0.42) | KMT2ACCR3LMNAMAPTGRM5 | |
| SCHEMBL17206710 | 0.90 | MEN1 (0.38) | SLC6A9MAPK14KMT2ALMNATP53 | |
| SCHEMBL9924330 | 0.89 | GRM5 (0.47) | MAPK14KMT2ACCR3GRM5L3MBTL1 | |
| SCHEMBL9924087 | 0.84 | HSD11B1 (0.39) | SLC6A9KMT2ALMNAMAPTL3MBTL1 | |
| SCHEMBL9924255 | 0.83 | GRM4 (0.36) | SLC6A9KMT2AMAPTGRM4EPHX2 | |
| SCHEMBL9924331 | 0.83 | NPC1 (0.40) | KMT2ACCR3LMNAMAPTGRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |
| WO-2012078867-A2 | CYCLOALKYL GUANIDINE F1F0-ATPASE INHIBITORS AND THERAPEUTIC USES THEREOF | LYCERA CORPORATION (US) | 2012-06-14 | — | — | WO | disclosed |