Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 5/20 | 0.40 |
| ▸ | RAF1 | P04049 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 2/20 | 0.40 |
| ▸ | BCR | P11274 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9924262 | 0.85 | UBE2M (0.46) | TRPV1ALDH1A1MEN1KMT2AMRGPRX4 | |
| SCHEMBL9924261 | 0.85 | TRPV1 (0.42) | TRPV1ALDH1A1MEN1KMT2AMRGPRX4 | |
| SCHEMBL9924227 | 0.84 | EPHX2 (0.52) | MEN1KMT2AEPHX2MAOB | |
| SCHEMBL17206706 | 0.82 | DCUN1D1 (0.52) | MEN1KMT2AEPHX2 | |
| SCHEMBL9924153 | 0.81 | TRPV1 (0.42) | TRPV1ALDH1A1MRGPRX4EPHX2 | |
| SCHEMBL17206619 | 0.79 | EPHX2 (0.48) | MEN1KMT2AEPHX2MAOB | |
| SCHEMBL18558524 | 0.78 | MEN1 (0.35) | TRPV1ALDH1A1MEN1KMT2AMRGPRX4 | |
| SCHEMBL19362654 | 0.77 | TRPV1 (0.42) | TRPV1MRGPRX4EPHX2 | |
| SCHEMBL9924130 | 0.77 | DCUN1D1 (0.52) | ALDH1A1MEN1KMT2AMRGPRX4EPHX2 | |
| SCHEMBL9924226 | 0.77 | EPHX2 (0.53) | MEN1KMT2AEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9169199-B2 | Cycloalkyl guanidine F1F0-ATPase inhibitors and therapeutic uses thereof | LYCERA CORPORATION (US) | 2015-10-27 | — | — | US | disclosed |