Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | PLG | P00747 | 1/20 | 0.41 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.41 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.41 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.41 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.41 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.41 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.41 |
| ▸ | NMUR2 | Q9GZQ4 | 1/20 | 0.39 |
| ▸ | NMUR1 | Q9HB89 | 1/20 | 0.39 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | NPY1R | P25929 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | NTSR2 | O95665 | 1/20 | 0.38 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9925691 | 0.79 | PLG (0.62) | F2PLGPRSS1PRSS2PRSS3 | |
| SCHEMBL13402533 | 0.67 | DPP4 (0.49) | NPY1R | |
| SCHEMBL13315233 | 0.66 | OPRD1 (0.56) | F2MAPK8MAPK9MAPK10OPRD1 | |
| SCHEMBL7617115 | 0.66 | MAPK8 (0.45) | F2MAPK8MAPK9MAPK10 | |
| SCHEMBL10058596 | 0.65 | NTSR1 (0.61) | MAPK8MAPK9MAPK10RENOPRD1 | |
| SCHEMBL29946190 | 0.65 | GZMB (0.52) | F2RENNPY1RNTSR2NTSR1 | |
| SCHEMBL22148957 | 0.64 | NPY1R (0.47) | F2NPY1ROPRD1NTSR2NTSR1 | |
| SCHEMBL30512666 | 0.63 | AGTR2 (0.55) | RENOPRD1NTSR2NTSR1 | |
| SCHEMBL3489108 | 0.63 | CASP3 (0.52) | F2RENNTSR2NTSR1 | |
| SCHEMBL6032452 | 0.63 | NPY1R (0.43) | F2RENNPY1R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070082377-A1 | Cytotoxicity assays | IMMUNOCHEMISTRY TECHNOLOGIES, LLC | 2007-04-12 | — | — | US | disclosed |
| US-20070082377-A1 | Cytotoxicity assays | IMMUNOCHEMISTRY TECHNOLOGIES, LLC | 2007-04-12 | — | — | US | disclosed |