Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.41 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.41 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.40 |
| ▸ | PLK2 | Q9NYY3 | 2/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1782340 | 0.79 | ADRB2 (0.48) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL28213904 | 0.79 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL13355960 | 0.79 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL277280 | 0.79 | ADRB2 (0.48) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL127127 | 0.78 | NPC1 (0.53) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL4659047 | 0.78 | NPC1 (0.46) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL28215701 | 0.78 | ADRB2 (0.47) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL2416629 | 0.77 | NPC1 (0.49) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL7628642 | 0.76 | NPC1 (0.47) | NPC1RAB9AMEN1KMT2AESR1 | |
| SCHEMBL14944464 | 0.75 | ADRB2 (0.44) | NPC1RAB9AMEN1KMT2AESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120148521-A1 | Methods and Compositions for Controlled Release of Drugs | THE UNIVERSITY OF WYOMING | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120148521-A1 | Methods and Compositions for Controlled Release of Drugs | OPRK1, OPRM1, AANAT | NPC1 4286/4885RAB9A 2398/4885MEN1 4569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.