Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 2/20 | 0.47 |
| ▸ | CCR5 | P51681 | 1/20 | 0.46 |
| ▸ | PARL | Q9H300 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.43 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7835509 | 0.73 | CCR5 (0.87) | CCR5 | |
| SCHEMBL1974783 | 0.72 | ALDH1A1 (0.85) | ALDH1A1GAAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL16030436 | 0.70 | L3MBTL1 (0.47) | ALDH1A1GAAKMT2AMEN1CCR5 | |
| SCHEMBL16030437 | 0.70 | L3MBTL1 (0.47) | ALDH1A1GAAKMT2AMEN1CCR5 | |
| SCHEMBL16030433 | 0.70 | L3MBTL1 (0.47) | ALDH1A1GAAKMT2AMEN1CCR5 | |
| SCHEMBL31681325 | 0.70 | GAA (0.68) | ALDH1A1GAAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL5407453 | 0.70 | ALDH1A1 (1.00) | ALDH1A1GAAKMT2ATSHRSMN1; SMN2 | |
| SCHEMBL7828983 | 0.70 | CCR5 (0.63) | ALDH1A1KMT2APOLBCCR5RAB9A | |
| SCHEMBL16033007 | 0.68 | PKM (0.52) | ALDH1A1KMT2ATSHRSMN1; SMN2MEN1 | |
| SCHEMBL16033005 | 0.68 | PKM (0.52) | ALDH1A1KMT2ATSHRSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1836180-B1 | SULFONYL PYRROLIDINES, METHOD FOR PRODUCING THE SAME AND THEIR USE AS DRUGS | SANOFI SA (FR) | 2012-06-13 | — | — | EP | disclosed |