SCHEMBL9512480

SCHEMBL9512480

CCOP(=O)(Cc1ccc(CO)cc1)OCC

nearest known ligand 0.45

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
PPARD Q03181 1/20 0.45
NPY5R Q15761 1/20 0.42
TSHR P16473 1/20 0.41
POLB P06746 2/20 0.40
MAPT P10636 2/20 0.40
HDAC1 Q13547 1/20 0.39
HTT P42858 1/20 0.39
CCNT1 O60563 2/20 0.38
CDK9 P50750 2/20 0.38
EGFR P00533 2/20 0.38
TLR8 Q9NR97 1/20 0.37
TLR7 Q9NYK1 1/20 0.37
PTK2 Q05397 1/20 0.36
PPARG P37231 1/20 0.36
PPARA Q07869 1/20 0.36
ENPP2 Q13822 1/20 0.36
MAPK1 P28482 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3375825 0.90 TSHR (0.50) PPARDNPY5RTSHRPOLBMAPT
SCHEMBL12891158 0.86 NPY5R (0.43) NPY5RTSHRPOLBMAPTHDAC1
SCHEMBL283016 0.85 EGFR (0.47) PPARDNPY5RTSHRPOLBMAPT
SCHEMBL13981237 0.85 ENPP2 (0.51) PPARDNPY5RTSHRPOLBMAPT
SCHEMBL16062693 0.84 POLB (0.46) PPARDNPY5RTSHRPOLBMAPT
SCHEMBL2493713 0.84 TSHR (0.44) PPARDNPY5RTSHRPOLBMAPT
SCHEMBL914644 0.83 EGFR (0.46) PPARDNPY5RTSHRPOLBMAPT
SCHEMBL23822678 0.82 TSHR (0.43) PPARDNPY5RTSHRPOLBMAPT
SCHEMBL915242 0.82 TSHR (0.43) PPARDNPY5RTSHRPOLBMAPT
SCHEMBL25923558 0.82 TSHR (0.43) PPARDNPY5RTSHRPOLBMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11674102-B2 Electrically-conductive lubricant UNIVERSITY OF YAMANASHI (JP) 2023-06-13 US disclosed
US-20210348078-A1 ELECTRICALLY-CONDUCTIVE LUBRICANT UNIVERSITY OF YAMANASHI (JP) 2021-11-11 US disclosed
US-9925153-B2 Therapeutic agents for skin diseases and conditions STC.UNM (US) 2018-03-27 US disclosed
US-20160287531-A1 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS STC.UNM 2016-10-06 US disclosed
US-8980954-B2 Substituted cis- and trans-stilbenes as therapeutic agents STC.UNM (US) 2015-03-17 US disclosed
US-20130178536-A1 SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS STC.UNM (US) 2013-07-11 US disclosed
US-20070249647-A1 Substituted CIS- and trans-stilbenes as therapeutic agents REGENTS OF THE UNIVERSITY OF NEW MEXICO 2007-10-25 US disclosed
EP-0313002-B1 Phenyl glycines for use in reducing neurotoxic injury SEARLE & CO (US) 1993-12-01 EP disclosed
US-4918064-A TREATMENT OF ANOXIA OR ISCHEMIA G. D. SEARLE & CO. (US) 1990-04-17 US disclosed
EP-0313002-A2 Phenyl glycines for use in reducing neurotoxic injury G.D. Searle & Co. (US) 1989-04-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160287531-A1 THERAPEUTIC AGENTS FOR SKIN DISEASES AND CONDITIONS CUTA, TSLP, ELANE PPARD 1606/4885NPY5R 3690/4885TSHR 4582/4885
US-20070249647-A1 Substituted CIS- and trans-stilbenes as therapeutic agents TGFB1, VHL, TMSB10 PPARD 102/4885NPY5R 4304/4885TSHR 3542/4885
US-20130178536-A1 SUBSTITUTED CIS- AND TRANS-STILBENES AS THERAPEUTIC AGENTS PSEN1, TERT, PSEN2 PPARD 194/4885NPY5R 3225/4885TSHR 4307/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.