Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | LMNA | P02545 | 2/20 | 0.30 |
| ▸ | TSHR | P16473 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.30 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4568620 | 0.95 | PDCD1 (0.32) | HTTGPR84 | |
| SCHEMBL4568712 | 0.93 | — | — | |
| SCHEMBL10102299 | 0.92 | PDCD1 (0.32) | — | |
| SCHEMBL10262650 | 0.91 | EDNRA (0.35) | MEN1KMT2AKDM4E | |
| SCHEMBL1009516 | 0.89 | PGR (0.32) | HTTPGRMEN1LMNATSHR | |
| SCHEMBL29664129 | 0.89 | PGR (0.32) | HTTPGRMEN1LMNATSHR | |
| SCHEMBL29664183 | 0.89 | PGR (0.34) | HTTGPR84PGRMEN1LMNA | |
| SCHEMBL1680041 | 0.89 | PGR (0.34) | HTTGPR84PGRMEN1LMNA | |
| SCHEMBL4568636 | 0.88 | — | — | |
| SCHEMBL9932623 | 0.88 | KDM4E (0.36) | HTTGPR84PGRMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120270071-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-10-25 | — | — | US | disclosed |
| US-20120161089-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20120145974-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120145974-A1 | CHROMENE COMPOUND | CRY2, CYP2J2, NR0B2 | HTT 2949/4885GPR84 2734/4885PGR 531/4885 |
| US-20120270071-A1 | CHROMENE COMPOUND | NR0B2, NR2C2, NR0B1 | HTT 3829/4885GPR84 2015/4885PGR 86/4885 |
| US-20120161089-A1 | CHROMENE COMPOUND | CYP8B1, HSD3B2, CYP17A1 | HTT 3687/4885GPR84 2210/4885PGR 64/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.