Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDCD1 | Q15116 | 1/20 | 0.32 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 2/20 | 0.31 |
| ▸ | EDNRB | P24530 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10102299 | 0.97 | PDCD1 (0.32) | PDCD1CD274 | |
| SCHEMBL9928121 | 0.95 | HTT (0.32) | HTTGPR84 | |
| SCHEMBL4568636 | 0.92 | — | — | |
| SCHEMBL29664129 | 0.91 | PGR (0.32) | HTT | |
| SCHEMBL1009516 | 0.91 | PGR (0.32) | HTT | |
| SCHEMBL10262650 | 0.91 | EDNRA (0.35) | EDNRAEDNRB | |
| SCHEMBL15763098 | 0.90 | PDCD1 (0.31) | PDCD1CD274 | |
| SCHEMBL1046559 | 0.89 | MEN1 (0.32) | HTT | |
| SCHEMBL29453311 | 0.89 | MEN1 (0.32) | HTT | |
| SCHEMBL4568712 | 0.89 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9588257-B2 | Photochromic curable composition | TOKUYAMA CORPORATION (JP) | 2017-03-07 | — | — | US | disclosed |
| US-20160116765-A1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2016-04-28 | — | — | US | disclosed |
| US-20150368552-A1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2015-12-24 | — | — | US | disclosed |
| US-20150030866-A1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2015-01-29 | — | — | US | disclosed |
| US-20140203226-A1 | (METH)ACRYLATE COMPOUND AND PHOTOCHROMIC CURABLE COMPOSITION CONTAINING THE (METH)ACRYLATE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-07-24 | — | — | US | disclosed |
| US-8778236-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2014-07-15 | — | — | US | disclosed |
| US-20140146285-A1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 2014-05-29 | — | — | US | disclosed |
| US-8709308-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2014-04-29 | — | — | US | disclosed |
| US-8691120-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2014-04-08 | — | — | US | disclosed |
| US-20140054520-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-02-27 | — | — | US | disclosed |
| US-20140034884-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2014-02-06 | — | — | US | disclosed |
| US-8308995-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2012-11-13 | — | — | US | disclosed |
| US-8308996-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2012-11-13 | — | — | US | disclosed |
| US-20120170098-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-07-05 | — | — | US | disclosed |
| US-20120138876-A1 | CHROMENE COMPOUND | KASAI SOKO (JP) | 2012-06-07 | — | — | US | disclosed |
| US-20120121934-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-05-17 | — | — | US | disclosed |
| US-8147726-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2012-04-03 | — | — | US | disclosed |
| US-20110062396-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2011-03-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140203226-A1 | (METH)ACRYLATE COMPOUND AND PHOTOCHROMIC CURABLE COMPOSITION CONTAINING THE (METH)ACRYLATE COMPOUND | TET1, MGMT, CRYAA | PDCD1 4267/4885CD274 3980/4885EDNRA 1015/4885 |
| US-20150368552-A1 | PHOTOCHROMIC CURABLE COMPOSITION | H1-0, CDH1, COL1A1 | PDCD1 3657/4885CD274 2423/4885EDNRA 2926/4885 |
| US-20120138876-A1 | CHROMENE COMPOUND | CHRM1, CBX8, CBX7 | PDCD1 535/4885CD274 446/4885EDNRA 570/4885 |
| US-20120170098-A1 | CHROMENE COMPOUND | CRY2, CRY1, SUN2 | PDCD1 599/4885CD274 920/4885EDNRA 2966/4885 |
| US-20110062396-A1 | CHROMENE COMPOUND | CDYL, NR0B1, NR1H2 | PDCD1 2577/4885CD274 2040/4885EDNRA 1011/4885 |
| US-20150030866-A1 | PHOTOCHROMIC CURABLE COMPOSITION | CRYAA, AHCY, WDR1 | PDCD1 4796/4885CD274 4600/4885EDNRA 2395/4885 |
| US-20120121934-A1 | CHROMENE COMPOUND | TST, CNOT1, CNOT9 | PDCD1 2805/4885CD274 2561/4885EDNRA 4337/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.