Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 1/20 | 0.31 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9928189 | 0.94 | HTR7 (0.32) | PARP1PDK2CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9928153 | 0.89 | MTNR1A (0.32) | PARP1 | |
| SCHEMBL9928185 | 0.88 | — | — | |
| SCHEMBL9928156 | 0.88 | PARP1 (0.30) | PARP1 | |
| SCHEMBL9928186 | 0.87 | STK17B (0.32) | PARP1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9928183 | 0.87 | LMNA (0.40) | PARP1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9928184 | 0.85 | PDK2 (0.31) | PDK2 | |
| SCHEMBL9928162 | 0.85 | KDM4E (0.33) | PARP1CYP1A1CYP1A2CYP1B1 | |
| SCHEMBL9928160 | 0.84 | PDK2 (0.32) | PDK2 | |
| SCHEMBL9928157 | 0.83 | FFAR4 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120145974-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |
| US-20120145974-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120145974-A1 | CHROMENE COMPOUND | CRY2, CYP2J2, NR0B2 | PARP1 2140/4885PDK2 703/4885CYP1A1 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.