Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.38 |
| ▸ | HRH1 | P35367 | 3/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1137366 | 0.98 | HTR2A (0.39) | HTR2AHRH1ALOX5CYP2C19TAAR1 | |
| Iodide SCHEMBL9934390 | 0.96 | HTR2A (0.38) | HTR2AHRH1ALOX5CYP2C19TAAR1 | |
| Hydrochloric Acid SCHEMBL1898617 | 0.96 | TDP1 (0.39) | HTR2AHRH1ALOX5CYP2C19TAAR1 | |
| SCHEMBL7166960 | 0.83 | ALOX5 (0.42) | ALOX5CYP2C19 | |
| SCHEMBL9933271 | 0.83 | RAB9A (0.39) | ALOX5CYP2C19ALDH1A1TDP1 | |
| SCHEMBL3259406 | 0.81 | HTR2A (0.42) | HTR2AHRH1ALOX5CYP2C19AOC3 | |
| SCHEMBL15389719 | 0.80 | HCAR2 (0.35) | ALOX5CYP2C19ALDH1A1TDP1 | |
| SCHEMBL4828076 | 0.79 | PYCR1 (0.47) | HTR2AHRH1ALOX5CYP2C19 | |
| SCHEMBL1628983 | 0.79 | — | — | |
| SCHEMBL4828058 | 0.79 | PYCR1 (0.47) | HTR2AHRH1ALOX5CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107075036-B | Polyacrylamide resin, papermaking additive and paper | HARIMA CHEMICALS, INC. (JP) | 2019-11-01 | — | — | CN | disclosed |
| CN-110003386-A | Polyacrylamide resin, additive for paper making and paper | 哈利玛化成株式会社 | 2019-07-12 | — | — | CN | disclosed |
| CN-107075036-A | Polyacrylamide resin, papermaking additive and paper | 哈利玛化成株式会社 | 2017-08-18 | — | — | CN | disclosed |
| US-9159352-B2 | Polishing liquid composition for magnetic disk substrate | KAO CORPORATION (JP) | 2015-10-13 | — | — | US | disclosed |
| CN-103503068-A | Manufacturing method of magnetic disk substrate | KAO CORP | 2014-01-08 | — | — | CN | disclosed |
| US-20140001155-A1 | MANUFACTURING METHOD OF MAGNETIC DISK SUBSTRATE | KAO CORPORATION (JP) | 2014-01-02 | — | — | US | disclosed |
| US-20130309946-A1 | METHOD FOR MANUFACTURING MAGNETIC DISC SUBSTRATE | KAO CORPORATION (JP) | 2013-11-21 | — | — | US | disclosed |
| CN-103339673-A | Method for manufacturing magnetic disc substrate | KAO CORP | 2013-10-02 | — | — | CN | disclosed |
| US-20120156968-A1 | POLISHING LIQUID COMPOSITION FOR MAGNETIC DISK SUBSTRATE | KAO CORPORATION (JP) | 2012-06-21 | — | — | US | disclosed |