Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | CTSB | P07858 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 2/20 | 0.51 |
| ▸ | CNR2 | P34972 | 3/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.50 |
| ▸ | P2RX1 | P51575 | 3/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.49 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30153175 | 0.82 | PARP1 (0.68) | CTSLPARP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL241785 | 0.82 | PARP1 (0.68) | CTSLPARP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL3660211 | 0.80 | CNR2 (0.71) | SRD5A2CES2CNR2CNR1P2RX1 | |
| SCHEMBL17894214 | 0.80 | SRD5A2 (0.73) | SRD5A2CES2CNR2CNR1P2RX1 | |
| SCHEMBL1237189 | 0.80 | SRD5A2 (0.79) | SRD5A2CES2CNR2CNR1P2RX1 | |
| Hydrochloric Acid SCHEMBL27869733 | 0.80 | PARP1 (0.65) | CTSLPARP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16180051 | 0.80 | CES2 (0.73) | SRD5A2CES2CNR2CNR1P2RX1 | |
| SCHEMBL3838580 | 0.78 | PARP1 (0.63) | CTSLPARP1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL2013121 | 0.77 | PARP1 (0.53) | CTSLCES2CNR2CNR1PARP1 | |
| SCHEMBL31081586 | 0.77 | CNR2 (0.66) | SRD5A2CES2CNR2CNR1P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651914-B1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL INC (US) | 2015-05-13 | — | — | EP | disclosed |
| US-8920928-B2 | Photochromic compounds and compositions | TRANSITIONS OPTICAL, INC. (US) | 2014-12-30 | — | — | US | disclosed |
| EP-2651914-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | Transitions Optical, Inc. (US) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012082999-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | WO | disclosed |
| US-20120156508-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | TRANSITIONS OPTICAL, INC. (US) | 2012-06-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120156508-A1 | PHOTOCHROMIC COMPOUNDS AND COMPOSITIONS | CRY2, CRY1, IPO4 | SRD5A2 1443/4885CTSL 4884/4885CTSB 4778/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.