Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 2/20 | 0.38 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.38 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.38 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.38 |
| ▸ | AKT1 | P31749 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | MTOR | P42345 | 1/20 | 0.35 |
| ▸ | PTGIR | P43119 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096979 | 0.85 | KMT2A (0.47) | MMP13CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1096980 | 0.85 | KMT2A (0.47) | MMP13CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1096720 | 0.83 | MMP13 (0.41) | MMP13CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL994016 | 0.83 | MMP13 (0.41) | MMP13CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL1096718 | 0.83 | MMP13 (0.41) | MMP13CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26409828 | 0.80 | TRPM8 (0.44) | MMP13CTSSCTSKGAAAAK1 | |
| SCHEMBL992429 | 0.79 | REN (0.43) | MMP13AKT1CTSSCTSKGAA | |
| SCHEMBL17776389 | 0.77 | CHRNB2 (0.44) | MMP13CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26390162 | 0.77 | MMP13 (0.44) | MMP13CHRNB2CHRNB4CHRNA3CHRNA4 | |
| SCHEMBL26393799 | 0.77 | MMP13 (0.42) | MMP13AKT1CTSSCTSKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011011483-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2011-01-27 | — | — | WO | disclosed |