SCHEMBL993696

SCHEMBL993696

CC(=O)c1ccc(CNC(=O)OCc2ccccc2)cc1

nearest known ligand 0.78

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 3/20 0.62
HDAC2 Q92769 2/20 0.62
HDAC3 O15379 1/20 0.62
PLAU P00749 1/20 0.61
NAMPT P43490 1/20 0.58
MAOB P27338 1/20 0.55
LMNA P02545 2/20 0.54
SMN1; SMN2 Q16637 2/20 0.54
TNKS O95271 2/20 0.52
TNKS2 Q9H2K2 2/20 0.52
TPSAB1 Q15661 1/20 0.52
TPSD1 Q9BZJ3 1/20 0.52
TPSG1 Q9NRR2 1/20 0.52
ALDH1A1 P00352 2/20 0.51
HTT P42858 2/20 0.51
L3MBTL1 Q9Y468 2/20 0.50
MAPT P10636 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL991841 0.88 HDAC1 (0.64) HDAC1HDAC2HDAC3PLAUNAMPT
Benzyl Benzylcarbamate SCHEMBL1136818 0.87 PLAU (0.70) HDAC1HDAC2HDAC3PLAUNAMPT
SCHEMBL4766309 0.87 SMN1; SMN2 (0.62) HDAC1HDAC2HDAC3PLAUNAMPT
Benzyl Benzylcarbamate SCHEMBL19810513 0.86 PLAU (0.68) HDAC1HDAC2HDAC3PLAUNAMPT
Benzyl Benzylcarbamate SCHEMBL9998166 0.86 PLAU (0.68) HDAC1HDAC2HDAC3PLAUNAMPT
Benzyl Benzylcarbamate SCHEMBL28413454 0.86 PLAU (0.68) HDAC1HDAC2HDAC3PLAUNAMPT
SCHEMBL5931079 0.85 PLAU (0.69) HDAC1HDAC2HDAC3PLAUNAMPT
SCHEMBL6558145 0.85 HDAC1 (0.62) HDAC1HDAC2HDAC3PLAUNAMPT
SCHEMBL14328797 0.85 L3MBTL1 (0.67) HDAC1HDAC2HDAC3PLAUNAMPT
SCHEMBL12203724 0.85 SMN1; SMN2 (0.66) HDAC1HDAC2HDAC3PLAUNAMPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2451776-B1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING INC (US) 2019-09-18 EP disclosed
US-9732047-B2 N-alkoxyamide conjugates as imaging agents LANTHEUS MEDICAL IMAGING, INC. (US) 2017-08-15 US disclosed
US-9732047-B2 N-alkoxyamide conjugates as imaging agents LANTHEUS MEDICAL IMAGING, INC. (US) 2017-08-15 US disclosed
US-9732047-B2 N-alkoxyamide conjugates as imaging agents LANTHEUS MEDICAL IMAGING, INC. (US) 2017-08-15 US disclosed
EP-2240206-B1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING INC (US) 2017-03-22 EP disclosed
EP-2240206-B1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING INC (US) 2017-03-22 EP disclosed
US-20170029386-A9 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2017-02-02 US disclosed
US-20170029386-A9 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2017-02-02 US disclosed
US-20170029386-A9 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2017-02-02 US disclosed
US-9393329-B2 N-alkoxyamide conjugates as imaging agents LANTHEUS MEDICAL IMAGING, INC. (US) 2016-07-19 US disclosed
US-20120328514-A1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2012-12-27 US disclosed
US-20120328514-A1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2012-12-27 US disclosed
EP-2451776-A2 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS Lantheus Medical Imaging, Inc. (US) 2012-05-16 EP disclosed
WO-2011005322-A2 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2011-01-13 WO disclosed
WO-2011005322-A2 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2011-01-13 WO disclosed
EP-2240206-A1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS Lantheus Medical Imaging, Inc. (US) 2010-10-20 EP disclosed
US-20090252676-A1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC (US) 2009-10-08 US disclosed
US-20090252676-A1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC (US) 2009-10-08 US disclosed
WO-2009089022-A1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2009-07-16 WO disclosed
WO-2009089022-A1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS LANTHEUS MEDICAL IMAGING, INC. (US) 2009-07-16 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170029386-A9 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS TNNT2, UACA, ELANE HDAC1 1298/4885HDAC2 947/4885HDAC3 1053/4885
US-20120328514-A1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS TNNT2, UACA, ELANE HDAC1 1298/4885HDAC2 947/4885HDAC3 1053/4885
US-20090252676-A1 N-ALKOXYAMIDE CONJUGATES AS IMAGING AGENTS TNNT2, UACA, ELANE HDAC1 1298/4885HDAC2 947/4885HDAC3 1053/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.