Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | IMPDH2 | P12268 | 2/20 | 0.39 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL99375 | 0.96 | NPC1 (0.49) | RAB9ANPC1KMT2ATSHRHDAC1 | |
| SCHEMBL99141 | 0.94 | NPC1 (0.48) | RAB9ANPC1KMT2ATSHRHDAC1 | |
| SCHEMBL102843 | 0.93 | HCAR2 (0.42) | RAB9ANPC1KMT2ATSHRHDAC1 | |
| SCHEMBL101812 | 0.89 | PTGDR2 (0.42) | RAB9ANPC1HDAC1HDAC2HCAR2 | |
| SCHEMBL100524 | 0.89 | RORC (0.43) | RAB9ANPC1KMT2ATSHRHDAC1 | |
| SCHEMBL102179 | 0.88 | NPC1 (0.42) | RAB9ANPC1KMT2ATSHRLMNA | |
| SCHEMBL99813 | 0.88 | HCAR2 (0.44) | RAB9AHDAC1HDAC2HCAR2 | |
| SCHEMBL100322 | 0.87 | HPGD (0.44) | RAB9ANPC1KMT2ATSHRHDAC1 | |
| SCHEMBL98766 | 0.86 | LTB4R (0.52) | KMT2ATSHRLTB4RSMN1; SMN2MEN1 | |
| SCHEMBL99091 | 0.86 | RAB9A (0.51) | RAB9ANPC1KMT2ATSHRHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2426121-A1 | QUATERNARY AMMONIUM SALT COMPOUND | Teijin Pharma Limited (JP) | 2012-03-07 | — | — | EP | claimed |