SCHEMBL9937778

SCHEMBL9937778

Cc1ccc(C(=O)NC[CH]C(C)C)cc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.53
POLB P06746 1/20 0.53
NPC1 O15118 5/20 0.50
RAB9A P51151 4/20 0.50
ALDH1A1 P00352 3/20 0.50
GAA P10253 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
HDAC1 Q13547 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
KMT2A Q03164 2/20 0.47
SMN1; SMN2 Q16637 3/20 0.46
TDP1 Q9NUW8 2/20 0.46
MMP13 P45452 1/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.45
KDM4E B2RXH2 1/20 0.45
HTT P42858 1/20 0.45
HPGD P15428 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
PKM P14618 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3993032 0.80 LMNA (0.62) LMNAPOLBNPC1RAB9AALDH1A1
SCHEMBL7208359 0.80 POLB (0.58) LMNAPOLBNPC1RAB9AALDH1A1
SCHEMBL16569104 0.79 LMNA (0.43) LMNAPOLBNPC1RAB9AALDH1A1
SCHEMBL9068167 0.79 PKM (0.68) LMNAPOLBNPC1RAB9AALDH1A1
SCHEMBL15566432 0.77 LMNA (0.54) LMNAPOLBNPC1RAB9AALDH1A1
SCHEMBL178516 0.77 MLYCD (0.65) LMNAPOLBNPC1RAB9AALDH1A1
SCHEMBL27887224 0.76 NPC1 (0.54) LMNAPOLBNPC1RAB9AALDH1A1
SCHEMBL11220601 0.75 LMNA (0.85) LMNAPOLBNPC1RAB9AALDH1A1
SCHEMBL24386356 0.75 LMNA (0.56) LMNAPOLBNPC1RAB9AALDH1A1
SCHEMBL5800429 0.75 LMNA (0.56) LMNAPOLBNPC1RAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2019197615-A1 ACTIVE INGREDIENT COMBINATIONS WITH FUNGICIDES, INSECTICIDES AND ACARICIDAL PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 2019-10-17 WO claimed
US-20170265470-A1 Anthranilamides in combination with fungicides BAYER INTELLECTUAL PROPERTY GMBH (DE) 2017-09-21 US claimed
EP-2892341-A2 ACTIVE COMPOUND COMBINATIONS Bayer CropScience AG (DE) 2015-07-15 EP claimed
EP-2892346-A2 ACTIVE COMPOUND COMBINATIONS Bayer CropScience AG (DE) 2015-07-15 EP claimed
WO-2014037314-A2 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2014-03-13 WO claimed
WO-2014037315-A2 ACTIVE COMPOUND COMBINATIONS BAYER CROPSCIENCE AG (DE) 2014-03-13 WO claimed
WO-2012082542-A2 SOYBEAN EVENT SYHT04R AND COMPOSITIONS AND METHODS FOR DETECTION THEREOF SYNGENTA PARTICIPATIONS AG (CH) 2012-06-21 WO claimed
EP-3107912-B1 DERIVATIVES OF 2-(HET)ARYL-SUBSTITUTED CONDENSED BICYCLIC HETEROCYCLES AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2024-07-10 EP disclosed
EP-4298908-A2 TRICYCLIC CARBOXAMIDES FOR THE CONTROL OF ARTHROPODS Bayer Animal Health GmbH (DE) 2024-01-03 EP disclosed
EP-3784661-B1 NOVEL HETEROARYL-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS AS PESTICIDES BAYER AG (DE) 2023-11-22 EP disclosed
EP-3601279-B1 TRICYCLIC CARBOXAMIDES AS CONTROL AGENT FOR ARTHROPODS BAYER ANIMAL HEALTH GMBH (DE) 2023-10-18 EP disclosed
EP-4203676-A1 TOMATO PLANTS WITH IMPROVED DISEASE RESISTANCE Seminis Vegetable Seeds, Inc. (US) 2023-07-05 EP disclosed
EP-4175961-A1 HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS Bayer Aktiengesellschaft (DE) 2023-05-10 EP disclosed
WO-2013124275-A1 USE OF SUCCINATE DEHYDROGENASE INHIBITORS (SDHIS) FOR CONTROLLING WOOD DISEASES IN GRAPE. BAYER CROPSCIENCE AG (DE) 2013-08-29 WO disclosed
WO-2013113742-A1 ACTIVE COMPOUND COMBINATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-08-08 WO disclosed
WO-2013107785-A1 USE OF HOST DEFENSE INDUCERS FOR CONTROLLING BACTERIAL HARMFUL ORGANISMS IN USEFUL PLANTS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-07-25 WO disclosed
WO-2013092519-A1 USE OF ANTHRANILIC ACID DIAMIDE DERIVATIVES FOR PEST CONTROL IN TRANSGENIC CROPS BAYER CROPSCIENCE AG (DE) 2013-06-27 WO disclosed
WO-2013064461-A2 COMPOUNDS WITH NEMATICIDAL ACTIVITY BAYER INTELLECTUAL PROPERTY GMBH (DE) 2013-05-10 WO disclosed
WO-2012168188-A1 ACTIVE COMPOUND COMBINATIONS BAYER INTELLECTUAL PROPERTY GMBH (DE) 2012-12-13 WO disclosed
WO-2012034957-A1 PESTICIDAL PYRROLINE N-OXIDE DERIVATIVES BAYER CROPSCIENCE AG (DE) 2012-03-22 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170265470-A1 Anthranilamides in combination with fungicides AADAC, ANTXR2, CYP51A1 LMNA 3681/4885POLB 4372/4885NPC1 3763/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.