Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.55 |
| ▸ | DBF4 | Q9UBU7 | 3/20 | 0.55 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | GABRP | O00591 | 1/20 | 0.38 |
| ▸ | GABRD | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1912617 | 0.87 | CDC7 (0.57) | CDC7DBF4SLC5A2HDAC3HDAC4 | |
| SCHEMBL3843901 | 0.85 | CDC7 (0.56) | CDC7DBF4SLC5A2HDAC3HDAC4 | |
| SCHEMBL1646493 | 0.84 | CDC7 (0.55) | CDC7DBF4SLC5A2HDAC3HDAC4 | |
| SCHEMBL5911684 | 0.84 | CDC7 (0.55) | CDC7DBF4SLC5A2HDAC3HDAC4 | |
| SCHEMBL4989265 | 0.84 | CDC7 (0.55) | CDC7DBF4SLC5A2HDAC3HDAC4 | |
| SCHEMBL11705050 | 0.83 | CDC7 (0.54) | CDC7DBF4SLC5A2HDAC3HDAC4 | |
| SCHEMBL15896622 | 0.83 | CDC7 (0.54) | CDC7DBF4SLC5A2HDAC3HDAC4 | |
| SCHEMBL3162147 | 0.81 | CDC7 (0.52) | CDC7DBF4SLC5A2HDAC3HDAC4 | |
| SCHEMBL28267334 | 0.81 | CDC7 (0.52) | CDC7DBF4SLC5A2HDAC3HDAC4 | |
| SCHEMBL21199675 | 0.80 | CDC7 (0.51) | CDC7DBF4SLC5A2HDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2651413-B1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | PHARMAHUNGARY 2000 KFT (HU) | 2017-11-22 | — | — | EP | disclosed |
| US-9487462-B2 | Inhibitors of matrix metalloproteinases | PHARMAHUNGARY 2000 KFT. (HU) | 2016-11-08 | — | — | US | disclosed |
| US-20130303572-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | TARGETEX KFT. (HU) | 2013-11-14 | — | — | US | disclosed |
| EP-2651413-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | Pharmahungary 2000 Kft. (HU) | 2013-10-23 | — | — | EP | disclosed |
| WO-2012080762-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | PHARMAHUNGARY 2000 KFT. (HU) | 2012-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130303572-A1 | NOVEL INHIBITORS OF MATRIX METALLOPROTEINASES | TIMP3, MMP3, MMP13 | CDC7 4838/4885DBF4 4165/4885SLC5A2 2494/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.