Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PLG | P00747 | 2/20 | 0.39 |
| ▸ | KLK1 | P06870 | 2/20 | 0.39 |
| ▸ | KLK6 | Q92876 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 5/20 | 0.39 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | AHR | P35869 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9944731 | 0.83 | FADS1 (0.53) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL9944974 | 0.82 | MAPT (0.47) | ALDH1A1TDP1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9944985 | 0.81 | KDR (0.35) | HSD17B10ALDH1A1NPC1RAB9AKMT2A | |
| SCHEMBL9946621 | 0.73 | PTGES (0.48) | TDP1NPC1SMN1; SMN2LMNAKMT2A | |
| SCHEMBL9899451 | 0.72 | FADS1 (0.50) | NPC1RAB9ASMN1; SMN2LMNAKMT2A | |
| SCHEMBL9945036 | 0.71 | ALDH1A1 (0.46) | HSD17B10ALDH1A1TDP1SMN1; SMN2LMNA | |
| SCHEMBL9944853 | 0.71 | ALOX15 (0.34) | ALDH1A1RAB9ALMNAHTTKDM4E | |
| SCHEMBL17327571 | 0.71 | MAPT (0.48) | HSD17B10ALDH1A1PLGKLK1KLK6 | |
| SCHEMBL9944977 | 0.70 | L3MBTL1 (0.41) | HSD17B10ALDH1A1TDP1NPC1RAB9A | |
| SCHEMBL9944979 | 0.70 | L3MBTL1 (0.41) | HSD17B10ALDH1A1TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | HSD17B10 941/4885ALDH1A1 126/4885TDP1 2131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.