Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.38 |
| ▸ | CFTR | P13569 | 10/20 | 0.37 |
| ▸ | CA12 | O43570 | 6/20 | 0.36 |
| ▸ | CA1 | P00915 | 6/20 | 0.36 |
| ▸ | CA2 | P00918 | 6/20 | 0.36 |
| ▸ | CA3 | P07451 | 6/20 | 0.36 |
| ▸ | CA4 | P22748 | 6/20 | 0.36 |
| ▸ | CA6 | P23280 | 6/20 | 0.36 |
| ▸ | CA5A | P35218 | 6/20 | 0.36 |
| ▸ | CA7 | P43166 | 6/20 | 0.36 |
| ▸ | CA9 | Q16790 | 6/20 | 0.36 |
| ▸ | CA13 | Q8N1Q1 | 6/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 6/20 | 0.36 |
| ▸ | CA5B | Q9Y2D0 | 6/20 | 0.36 |
| ▸ | PRKCI | P41743 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9946982 | 0.88 | SPR (0.38) | POLBAPEX1CFTRCA12CA1 | |
| SCHEMBL30739976 | 0.77 | P2RX7 (0.51) | CFTRCA12CA1CA2CA9 | |
| SCHEMBL20051338 | 0.77 | P2RX7 (0.51) | CFTRCA12CA1CA2CA9 | |
| SCHEMBL12495108 | 0.76 | LOXL2 (0.40) | POLBAPEX1CA12CA1CA2 | |
| SCHEMBL9944999 | 0.76 | KDM4E (0.39) | POLBTDP1 | |
| SCHEMBL9944992 | 0.76 | PTGES (0.40) | CFTR | |
| SCHEMBL9946610 | 0.72 | PTGES (0.50) | — | |
| SCHEMBL23577708 | 0.71 | GAA (0.51) | POLBCFTRPRKCI | |
| SCHEMBL20051344 | 0.70 | P2RX7 (0.38) | POLBAPEX1CFTRCA12CA1 | |
| SCHEMBL30739680 | 0.70 | P2RX7 (0.38) | POLBAPEX1CFTRCA12CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8674113-B2 | Compounds | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2014-03-18 | — | — | US | disclosed |
| US-20120149676-A1 | NOVEL COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149676-A1 | NOVEL COMPOUNDS | PTGS1, PTGER1, PTGES | POLB 2315/4885APEX1 2510/4885CFTR 1466/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.